SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications
E Brown, HJL Heerspink, DJ Cuthbertson, JPH Wilding - The Lancet, 2021 - thelancet.com
SGLT2 inhibitors and GLP-1 receptor agonists are used in patients with type 2 diabetes as
glucose lowering therapies, with additional benefits of weight loss and blood pressure …
glucose lowering therapies, with additional benefits of weight loss and blood pressure …
[HTML][HTML] Treatment options for alcoholic and non-alcoholic fatty liver disease: A review
S Singh, NA Osna, KK Kharbanda - World journal of …, 2017 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious
health problems worldwide. These two diseases have similar pathological spectra, ranging …
health problems worldwide. These two diseases have similar pathological spectra, ranging …
Efficacy and safety of once-weekly semaglutide 1.0 mg vs once-daily liraglutide 1.2 mg as add-on to 1–3 oral antidiabetic drugs in subjects with type 2 diabetes …
MS Capehorn, AM Catarig, JK Furberg, A Janez… - Diabetes & …, 2020 - Elsevier
Aims SUSTAIN 10 compared the efficacy and safety of the anticipated most frequent
semaglutide dose (1.0 mg) with the current most frequently prescribed liraglutide dose in …
semaglutide dose (1.0 mg) with the current most frequently prescribed liraglutide dose in …
Epigenetics in NAFLD/NASH: Targets and therapy
Recently non-alcoholic fatty liver disease (NAFLD) has grabbed considerable scientific
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …
GLP-1/glucagon receptor co-agonism for treatment of obesity
MA Sánchez-Garrido, SJ Brandt, C Clemmensen… - Diabetologia, 2017 - Springer
Over a relatively short period, obesity and type 2 diabetes have come to represent a large
medical and economic burden to global societies. The epidemic rise in the prevalence of …
medical and economic burden to global societies. The epidemic rise in the prevalence of …
GLP-1 receptor agonists in the treatment of type 2 diabetes: role and clinical experience to date
SA Brunton, CH Wysham - Postgraduate medicine, 2020 - Taylor & Francis
ABSTRACT Glucagon-like peptide-1 (GLP-1) is a hormone of the incretin system
responsible for a variety of glucoregulatory effects, including glucose-dependent secretion of …
responsible for a variety of glucoregulatory effects, including glucose-dependent secretion of …
Neural correlates of liraglutide effects in persons at risk for Alzheimer's disease
Insulin resistance (IR) is a metabolic state preceding development of type 2 diabetes (DM2),
cardiovascular disease, and neurodegenerative disorders, including Alzheimer's Disease …
cardiovascular disease, and neurodegenerative disorders, including Alzheimer's Disease …
Long-term effectiveness of liraglutide for weight management and glycemic control in type 2 diabetes
M Mirabelli, E Chiefari, P Caroleo… - International Journal of …, 2020 - mdpi.com
Background: Liraglutide is the first glucagon-like peptide-1 receptor agonist (GLP-1 RA)
based on the human GLP-1 sequence, with potential weight loss benefits, approved for the …
based on the human GLP-1 sequence, with potential weight loss benefits, approved for the …
Liraglutide in combination with metformin may improve the atherogenic lipid profile and decrease C-reactive protein level in statin treated obese patients with coronary …
C Anholm, P Kumarathurai, LR Pedersen, A Samkani… - Atherosclerosis, 2019 - Elsevier
Background and aims Atherosclerosis in obesity and type 2 diabetes (T2DM) is associated
with low-grade inflammation (LGI) and dyslipidemia, where especially small, dense …
with low-grade inflammation (LGI) and dyslipidemia, where especially small, dense …
Cardiovascular outcome studies in type 2 diabetes: comparison between SGLT2 inhibitors and GLP-1 receptor agonists
AJ Scheen - Diabetes Research and Clinical Practice, 2018 - Elsevier
Sodium-glucose cotransporter type 2 inhibitors (SGLT2is) and glucagon-like peptide-1
receptor agonists (GLP-1RAs) are two pharmacological classes that have proven their …
receptor agonists (GLP-1RAs) are two pharmacological classes that have proven their …