Objectives: Cardiac magnetic resonance (CMR) was used to investigate the extracellular
compartment and myocardial fibrosis in patients with aortic stenosis, as well as their …

Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Background Myocardial fibrosis is a key mechanism of left ventricular decompensation in
aortic stenosis and can be quantified using cardiovascular magnetic resonance (CMR) …

Aims Haemodynamics alone do not fully explain symptoms and prognosis in clinically
severe aortic stenosis (AS). Myocardial disease, specifically diffuse myocardial fibrosis …

Aims To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS)
patients using invasive biopsy and non-invasive imaging. Methods and results One hundred …

Objectives: This study assessed diffuse myocardial fibrosis (MF) by cardiac magnetic
resonance (CMR) imaging and speckle-tracking echocardiography (STE) in patients with …

Objectives: We sought to determine whether the quantitative assessment of myocardial
fibrosis (MF), either by histopathology or by contrast-enhanced magnetic resonance imaging …

Background: Left ventricular (LV) hypertrophy, a key process in human cardiac disease,
results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis) …

Purpose To assess whether native T1 mapping provides noninvasive estimation of diffuse
myocardial fibrosis and whether it correlates with subclinical myocardial dysfunction in …

Background: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and
fibrosis. We investigated the natural history of these processes in asymptomatic patients and …