Favipiravir: pharmacokinetics and concerns about clinical trials for 2019‐nCoV infection

YX Du, XP Chen - Clinical Pharmacology & Therapeutics, 2020 - Wiley Online Library
An outbreak of 2019‐nCoV infection has spread across the world. No specific antiviral drugs
have been approved for the treatment of COVID‐2019. In addition to the recommended …

Favipiravir and COVID-19: a simplified summary

M Ghasemnejad-Berenji, S Pashapour - Drug research, 2021 - thieme-connect.com
A recent outbreak of coronavirus disease 2019 (COVID-19) caused by the novel coronavirus
designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in …

[HTML][HTML] A review of the safety of favipiravir–a potential treatment in the COVID-19 pandemic?

V Pilkington, T Pepperrell, A Hill - Journal of virus eradication, 2020 - Elsevier
Background Repurposing broad-spectrum antivirals is an immediate treatment opportunity
for 2019 coronavirus disease (COVID-19). Favipiravir is an antiviral previously indicated for …

[HTML][HTML] Role of favipiravir in the treatment of COVID-19

S Joshi, J Parkar, A Ansari, A Vora, D Talwar… - International Journal of …, 2021 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) outbreak all over the world has led the
researchers to strive to develop drugs or vaccines to prevent or halt the progression of this …

Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model

JS Driouich, M Cochin, G Lingas, G Moureau… - Nature …, 2021 - nature.com
Despite no or limited pre-clinical evidence, repurposed drugs are massively evaluated in
clinical trials to palliate the lack of antiviral molecules against SARS-CoV-2. Here we use a …

Favipiravir in therapy of viral infections

R Łagocka, V Dziedziejko, P Kłos, A Pawlik - Journal of clinical medicine, 2021 - mdpi.com
Favipiravir (FPV) is a novel antiviral drug acting as a competitive inhibitor of RNA-dependent
RNA polymerase (RdRp), preventing viral transcription and replication. FPV was approved …

Favipiravir for treatment of outpatients with asymptomatic or uncomplicated coronavirus disease 2019: a double-blind, randomized, placebo-controlled, phase 2 trial

M Holubar, A Subramanian, N Purington… - Clinical Infectious …, 2022 - academic.oup.com
Background Favipiravir, an oral, RNA-dependent RNA polymerase inhibitor, has in vitro
activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite …

A review on favipiravir: the properties, function, and usefulness to treat COVID-19

SMR Hashemian, T Farhadi… - Expert review of anti …, 2021 - Taylor & Francis
Introduction At this time, there is no specific therapeutic or vaccine for treatment of the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, available drugs for …

Antiviral therapy for COVID-19: Derivation of optimal strategy based on past antiviral and favipiravir experiences

K Shiraki, N Sato, K Sakai, S Matsumoto… - Pharmacology & …, 2022 - Elsevier
Favipiravir, a broad-spectrum RNA-dependent RNA polymerase inhibitor, inhibits the
replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at …

Favipiravir for the treatment of patients with COVID-19: a systematic review and meta-analysis

T Manabe, D Kambayashi, H Akatsu, K Kudo - BMC infectious diseases, 2021 - Springer
Background Favipiravir possesses high utility for treating patients with COVID-19. However,
research examining the efficacy and safety of favipiravir for patients with COVID-19 is …