The present study evaluated the safety and efficacy of patient-activated delivery of
intrathecal morphine sulfate boluses delivered by way of a novel internalized intrathecal …

Background: Various methods exist for trialing patients for intrathecal drug delivery.
Currently no standards exist regarding “best practices” for trialing techniques. Objectives …

We have treated 37 patients with intractable pain (35 with cancer-related pain) by
continuous intrathecal morphine infusion via implanted pump. These patients were carefully …

OBJECTIVE: To examine in a prospective manner the long-term safety and efficacy of
chronic intrathecal morphine in patients with severe, nonmalignant pain refractory to less …

Objective. Long-term follow-up with the use of low-dose opioids in intrathecal (IT) drug
delivery system (DDS) for the treatment of intractable, severe chronic nonmalignant pain …

Background: The introduction of intrathecal opioid administration for intractable chronic non-
malignant pain and cancer pain is considered as one of the most important breakthroughs in …

Long-term intraspinal infusions of opioid drugs are being increasingly utilized in patients
with noncancer pain. Despite this, there is a lack of long-term information, including success …

Ten patients with intractable pain (five cancer and five nonmalignant) were treated with
continuous intraspinal morphine delivered by an implanted continuous infusion system. Both …

Objective This study aimed to investigate the efficacy of intrathecal morphine in the long term
by hypothesising that a reduction of the intrathecal opioid dose following long-term …

Intraspinal opioids are frequently used in the treatment of cancer and noncancer pain, but
few studies have evaluated the efficacy of this technique. This multicenter, retrospective …