Introduction Within the core neuroimaging signature of amyotrophic lateral sclerosis (ALS),
the corpus callosum (CC) is increasingly recognized as a consistent feature. The aim of this …

Purpose To determine if decline in corpus callosum (CC) white matter integrity in patients
with amyotrophic lateral sclerosis (ALS) is localized to motor‐related areas. Materials and …

Diffusion tensor imaging (DTI) has become a useful tool for investigating early white matter
(WM) abnormalities in motor neuron disease. Furthermore, fiber tracking packages that …

Background The regional distribution of cerebral morphological alterations in primary lateral
sclerosis (PLS) is considered to include the area III of the corpus callosum (CC). Objective …

Objective: While the hallmark of amyotrophic lateral sclerosis (ALS) is corticospinal tract in
combination with lower motor neuron degeneration, the clinical involvement of both …

Background and Purpose Involvement of the corpus callosum (CC) is reported to be a
consistent feature of amyotrophic lateral sclerosis (ALS). We examined the CC pathology …

Abstract Background and Objectives: The corpus callosum is a site of pathological
involvement in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS). The …

Neurodegenerative process in amyotrophic lateral sclerosis (ALS) has been proven to
involve several cortical and subcortical brain regions within and beyond motor areas …

Background There is an ongoing debate about the concept of restricted phenotypes of
amyotrophic lateral sclerosis (ALS), including progressive bulbar palsy (PBP). Objective The …

We investigated the frequency and functional relevance of corpus callosum degeneration in
amyotrophic lateral sclerosis (ALS). A total of 22 ALS patients and 29 healthy controls …