The effects of remifentanil on cerebral capacity in awake volunteers

IH Lorenz, C Kolbitsch, C Hörmann… - Anesthesia & …, 2000 - journals.lww.com
Remifentanil, a short-acting potent μ-opioid agonist proposed for intraoperative analgesia
but also for postoperative pain therapy, has not been investigated with regard to the effects …

Remifentanil and the brain

V Fodale, D Schifilliti, C Pratico… - Acta …, 2008 - Wiley Online Library
Background and aim: Remifentanil is an ultra‐short‐acting opioid, increasingly used today
in neuroanesthesia and neurointensive care. Its characteristics make remifentanil a …

Intracranial pressure and hemodynamic effects of remifentanil versus alfentanil in patients undergoing supratentorial craniotomy

DS Warner, BJ Hindman, MM Todd… - Anesthesia & …, 1996 - journals.lww.com
Remifentanil hydrochloride is an ultra-short-acting esterase metabolized mu-opioid receptor
agonist. The purpose of this study was to provide preliminary information regarding the …

Effect of remifentanil on intracranial pressure and cerebral blood flow velocity in patients with head trauma

K Engelhard, W Reeker, E Kochs… - Acta anaesthesiologica …, 2004 - Wiley Online Library
Background: Remifentanil, an ultra‐short‐acting opioid, is used as an on‐top analgesic in
head trauma patients during transient painful procedures, eg endotracheal suctioning …

Low‐dose remifentanil increases regional cerebral blood flow and regional cerebral blood volume, but decreases regional mean transit time and regional …

IH Lorenz, C Kolbitsch, M Schocke… - British journal of …, 2000 - academic.oup.com
We have used contrast media‐enhanced perfusion magnetic resonance imaging MRI to
measure regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV) …

Safety and feasibility of continuous infusion of remifentanil in the neurosurgical intensive care unit

LB Tipps, WM Coplin, KR Murry, DH Rhoney - Neurosurgery, 2000 - journals.lww.com
OBJECTIVE: Remifentanil is a selective μ-opioid agonist with a context-sensitive half-time of
3 to 5 minutes, independent of dose or administration duration. Other desirable effects …

Experience with remifentanil in neurosurgical patients

DS Warner - Anesthesia & Analgesia, 1999 - journals.lww.com
When a new drug is introduced into neuroanesthesia practice, several considerations must
be addressed. A principal concern is drug effect on cerebral perfusion pressure (CPP) …

The effect of remifentanil on cerebral blood flow velocity

A Paris, J Scholz, G von Knobelsdorff… - Anesthesia & …, 1998 - journals.lww.com
In the present study, we investigated the effect of remifentanil on cerebral blood flow velocity
(CBFV). We investigated 20 patients (ASA physical status III) scheduled for elective coronary …

The influence of nitrous oxide and remifentanil on cerebral hemodynamics in conscious human volunteers

IH Lorenz, C Kolbitsch, C Hörmann, TJ Luger… - Neuroimage, 2002 - Elsevier
Remifentanil is increasingly used in the context of anesthesia, eg, in patients presenting for
MRI examinations, not only as an analgesic but also to replace nitrous oxide. Therefore, a …

Dose-dependent regional cerebral blood flow changes during remifentanil infusion in humans: a positron emission tomography study

KJ Wagner, F Willoch, EF Kochs… - The Journal of the …, 2001 - pubs.asahq.org
Background The current study investigated dose-dependent effects of the mu-selective
agonist remifentanil on regional cerebral blood flow (rCBF) in volunteers using positron …