Objective: To perform a systematic review of the present scientific literature on the treatment
with methadone or buprenorphine related to (1) traffic accident risk in epidemiological …

Aims: To assess the influence of methadone and buprenorphine maintenance treatment on
the driving aptitude of opioid-dependent patients. Design: Prospective, open label …

In many European countries the use of opioids for long-term treatment of nonmalignant pain
has dramatically increased during the last decade in order to improve the patient's quality of …

Previous reviewers have concluded that opioids cause dose-related impairment in opioid-
naive volunteers on psychomotor skills related to driving. Data relating to opioid …

BACKGROUND: Opioids have been shown to impair psychomotor and cognitive functioning
in healthy volunteers with no history of opioid abuse. Few or no significant effects have been …

While methadone is currently the primary pharmacotherapy used in the treatment of heroin
dependence in Australia, levo-alpha-acetyl-methodol (LAAM) and buprenorphine are new …

Introduction The USA is in an opioid epidemic, with an increased number of individuals
taking psychoactive drugs while executing the tasks of everyday life, including operating a …

Aims The present study assessed the acute effects of methadone and buprenorphine on
actual on‐road driving performance and neurocognitive function. Methods Methadone (5 …

Opioid maintenance therapy is a well-established first-line treatment approach in opioid
dependence. The effects of opioids such as buprenorphine on cognitive functioning and …

To evaluate driving aptitude and traffic-relevant performance at peak and trough medication
levels in opioid-dependent patients receiving maintenance therapy with either …