Although we acknowledge the academic achievements of large descriptive studies, an
unmet priority of neuroimaging in MND is the development of robust diagnostic, prognostic …

The changing landscape of motor neuron disease imaging: the... : Current Opinion in
Neurology The changing landscape of motor neuron disease imaging: the transition from …

It is agreed that conventional magnetic resonance imaging (MRI) of the brain and spine is
one of the core elements in the differential diagnostic work up of patients with clinical signs …

Motor neuron diseases (MNDs) encompass a range of progressive neurodegenerative
conditions with heterogeneous clinical presentations, disability profiles, prognosis, and age …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Background Clinical phenotypic heterogeneity represents a major barrier to trials in motor
neuron disease (MND) and objective surrogate outcome measures are required, especially …

Two new studies highlight the potential of neuroimaging to aid the differential diagnosis of
neurodegenerative disease, for both clinical practice and emerging trials. Although this …

Motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (ALS), are a group of
devastating and progressive neurodegenerative disorders that affect the upper and lower …

The interest and research into disease-related biomarkers has greatly accelerated over the
last 10 years. The potential clinical benefits for disease-specific biomarkers include a more …

Magnetic resonance spectroscopy (MRS) has contributed important academic insights in
motor neuron diseases (MNDs), particularly in amyotrophic lateral sclerosis (ALS). Over the …