Ligand binding strategies of human serum albumin: how can the cargo be utilized?
Human serum albumin (HSA), being the most abundant carrier protein in blood and a
modern day clinical tool for drug delivery, attracts high attention among biologists. Hence, its …
modern day clinical tool for drug delivery, attracts high attention among biologists. Hence, its …
Stereoselective binding of human serum albumin
VTG Chuang, M Otagiri - Chirality: The Pharmacological …, 2006 - Wiley Online Library
Stereoselectivity in binding can have a significant effect on the drug disposition such as first‐
pass metabolism, metabolic clearance, renal clearance, and protein and tissue binding …
pass metabolism, metabolic clearance, renal clearance, and protein and tissue binding …
[HTML][HTML] Interactive association of drugs binding to human serum albumin
Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …
the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their …
Structural basis of drug recognition by human serum albumin
L Leboffe, A di Masi, F Polticelli… - Current medicinal …, 2020 - ingentaconnect.com
Background: Human serum albumin (HSA), the most abundant protein in plasma, is a
monomeric multi-domain macromolecule with at least nine binding sites for endogenous …
monomeric multi-domain macromolecule with at least nine binding sites for endogenous …
Structure, enzymatic activities, glycation and therapeutic potential of human serum albumin: A natural cargo
G Rabbani, SN Ahn - International journal of biological macromolecules, 2019 - Elsevier
Human serum albumin (HSA) is an opulent, non-glycosylated, most versatile carrier protein
in plasma possessing multiple functions. HSA has the ability to interact with a variety of …
in plasma possessing multiple functions. HSA has the ability to interact with a variety of …
Drug binding to human serum albumin: Abridged review of results obtained with high‐performance liquid chromatography and circular dichroism
GA Ascoli, E Domenici… - … , Biological, and Chemical …, 2006 - Wiley Online Library
The drug binding to plasma and tissue proteins are fundamental factors in determining the
overall pharmacological activity of a drug. Human serum albumin (HSA), together with α1 …
overall pharmacological activity of a drug. Human serum albumin (HSA), together with α1 …
Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy
Albumin is the most abundant circulating protein in plasma and has recently emerged as a
versatile protein carrier for drug targeting and for improving the pharmacokinetic profile of …
versatile protein carrier for drug targeting and for improving the pharmacokinetic profile of …
Serum albumin: Clinical significance of drug binding and development as drug delivery vehicle
Human serum albumin, the primary transport and reservoir protein in the human circulatory
system, interacts with numerous endogenous and exogenous ligands of varying structural …
system, interacts with numerous endogenous and exogenous ligands of varying structural …
The extraordinary ligand binding properties of human serum albumin
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes
of ligands at multiple sites. HSA provides a depot for many compounds, affects …
of ligands at multiple sites. HSA provides a depot for many compounds, affects …
Reversible and covalent binding of drugs to human serum albumin: methodological approaches and physiological relevance
C Bertucci, E Domenici - Current medicinal chemistry, 2002 - ingentaconnect.com
Human serum albumin (HSA) plays a fundamental role in the transport of drugs, metabolites,
and endogenous ligands. Binding to HSA controls the free, active concentration of a drug …
and endogenous ligands. Binding to HSA controls the free, active concentration of a drug …
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