[HTML][HTML] Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: relationship to exercise capacity, cumulative dose and …

EB Tham, MJ Haykowsky, K Chow, M Spavor… - Journal of …, 2013 - Elsevier
Background The late cardiotoxic effects of anthracycline chemotherapy influence morbidity
and mortality in the growing population of childhood cancer survivors. Even with lower …

Occult cardiotoxicity in childhood cancer survivors exposed to anthracycline therapy

OH Toro-Salazar, E Gillan, MT O'Loughlin… - Circulation …, 2013 - Am Heart Assoc
Background—More than 50% of> 270 000 childhood cancer survivors in the United States
have been treated with anthracyclines and are therefore at risk of developing cardiotoxicity …

Cardiac magnetic resonance imaging in the evaluation of the late effects of anthracyclines among long-term survivors of childhood cancer

K Ylänen, T Poutanen, P Savikurki-Heikkilä… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to examine the left ventricular (LV) and right ventricular (RV)
function and signs of focal fibrosis among long-term survivors of childhood cancer with the …

Anthracycline-induced cardiotoxicity: cardiac MRI after treatment for childhood cancer

K Oberholzer, RP Kunz, M Dittrich… - RoFo: Fortschritte auf …, 2004 - europepmc.org
Purpose Quantification of left and right ventricular function using MRI in young cancer
patients treated with cardiotoxic anthracyclines. Materials and methods Twenty-eight …

Native myocardial T1 time can predict development of subsequent anthracycline‐induced cardiomyopathy

F Muehlberg, S Funk, L Zange… - ESC heart …, 2018 - Wiley Online Library
Aims This study aims to assess subclinical changes in functional and morphological
myocardial magnetic resonance parameters very early into an anthracycline treatment …

Anthracycline therapy is associated with cardiomyocyte atrophy and preclinical manifestations of heart disease

T Ferreira de Souza, T Quinaglia AC Silva… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The goal of this study was to demonstrate that cardiac magnetic resonance could
reveal anthracycline-induced early tissue remodeling and its relation to cardiac dysfunction …

Echocardiographic assessment of cardiac function in pediatric survivors of anthracycline-treated childhood cancer

MG Slieker, C Fackoury, C Slorach, W Hui… - Circulation …, 2019 - Am Heart Assoc
Background: Anthracycline-induced cardiotoxicity is a major cause of morbidity and mortality
in childhood cancer survivors (CCSs). Echocardiographic myocardial strain imaging is …

[HTML][HTML] Subclinical cardiac dysfunction in childhood cancer survivors on 10-years follow-up correlates with cumulative anthracycline dose and is best detected by …

CM Wolf, B Reiner, A Kühn, A Hager, J Müller… - Frontiers in …, 2020 - frontiersin.org
Background: Survivors of childhood cancer are at risk for anthracycline-and/or radiotherapy-
induced cardiotoxicity. Aims: The aim of this study was to assess clinical, laboratory, and …

Subclinical cardiotoxicity in childhood cancer survivors exposed to very low dose anthracycline therapy

K Leger, T Slone, M Lemler, D Leonard… - Pediatric blood & …, 2015 - Wiley Online Library
Background Subclinical cardiotoxicity occurs in childhood cancer survivors following
moderate and high anthracycline doses. However, less is known about the subclinical …

Subclinical cardiac dysfunction and exercise performance in childhood cancer survivors

E De Caro, A Smeraldi, G Trocchio… - Pediatric blood & …, 2011 - Wiley Online Library
Background Although anthracycline cardiotoxicity is clearly related to the cumulative dose
administered, subclinical cardiac dysfunction has been reported across a wide range of …