Understanding drug fingerprints in complex biological samples is essential for the
development of a drug. Hyperspectral coherent anti-Stokes Raman scattering (HS-CARS) …

Microscopy-based high-content and high-throughput analysis of cellular systems plays a
central role in drug discovery. However, for contrast and specificity, the majority of assays …

Quantitative hyperspectral coherent Raman scattering microscopy merges imaging with
spectroscopy and utilises quantitative data analysis algorithms to extract physically …

Detailed spatial information of low–molecular weight compound distribution, especially in
the brain, is crucial to understanding their mechanism of actions. Imaging techniques that …

Spatial and spectral information of a nanocarrier and its payload is crucial for the
advancement of luminescence‐based imaging, disease detection, and treatment in complex …

Protein imaging aids diagnosis and drug development by revealing protein–drug
interactions or protein levels. However, the challenges of imaging multiple proteins, reduced …

Visualizing the presence and distribution of multiple specific molecular markers within a
tumor can reveal the composition of its microenvironment, inform diagnosis, stratify patients …

Visualizing live-cell uptake of small-molecule drugs is paramount for drug development and
pharmaceutical sciences. Bioorthogonal imaging with click chemistry has made significant …

Multiplexed detection and quantification of structurally similar drug molecules,
methylxanthine MeX, incl. theobromine TBR, theophylline TPH and caffeine CAF, have been …

Surface-enhanced Raman spectroscopy (SERS), providing near-single-molecule-level
fingerprint information, is a powerful tool for the trace analysis of a target in a complicated …