Cholinergic receptor blockade in the rat impairs locale but not taxon strategies for place navigation in a swimming pool.

IQ Whishaw - Behavioral neuroscience, 1985 - psycnet.apa.org
Normal rats and rats drugged with atropine sulfate, a cholinergic muscarinic blocker, were
evaluated in the Morris water task for their use of spatial navigation strategies. Atropine …

Formation of a place learning-set by the rat: a new paradigm for neurobehavioral studies

IQ Whishaw - Physiology & Behavior, 1985 - Elsevier
The Morris water swimming task provides an ideal way of studying spatial navigational
abilities in rats. It requires that rats swim to find a platform located just below the surface of …

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

IQ Whishaw, SB Dunnett - Behavioural brain research, 1985 - Elsevier
Rats depleted of dopamine by intraventricular or nigrostriatal bundle 6-hydroxydopamine
injection were compared with normal rats on acquisition and retention of place and cue …

Disruption of central cholinergic systems in the rat by basal forebrain lesions or atropine: effects on feeding, sensorimotor behaviour, locomotor activity and spatial …

IQ Whishaw, WT O'connor, SB Dunnett - Behavioural brain research, 1985 - Elsevier
Rats with ibotenic acid lesions of the nucleus basalis magnocellularis, the origin of the
extrinsic cholinergic innervation of the cortex, were examined for changes in feeding …

Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis—II. Sensorimotor and learning …

SB Dunnett, G Toniolo, A Fine, CN Ryan, A Björklund… - Neuroscience, 1985 - Elsevier
The cholinergic projection from the nucleus basalis magnocellularis to the neocortex has
been implicated in normal memory function and in the dementia of Alzheimer's disease. In …

Effects of lesions of prefrontal cortex and dorsomedial thalamus on delayed go/no-go alternation in rats

Y Sakurai, S Sugimoto - Behavioural Brain Research, 1985 - Elsevier
The effect of prefrontal cortex (PFC) and/or dorsomedial thalamus (DMT) lesions on a
delayed go/no-go alternation task was studied in the rat. The lesion gave rise to the …

Performance of hippocampectomized rats in a reference/working-memory task: Effects of preoperative versus postoperative training

PD Gage - Physiological psychology, 1985 - Springer
Hippocampectomized and sham-operated male rats were pre-or postoperatively trained to
perform a reference/working-memory task in a standard radial eight-arm maze. On each trial …

Perinatal glucocorticoids alter dentate gyrus electrophysiology

JP Vicedomini, AJ Nonneman, ST DeKosky… - Brain Research …, 1985 - Elsevier
Perinatal glucocorticoid administration produces permanent spatial discrimination learning
deficits in rats, presumably referable to changes in the development of neural systems …

Post-trial flicker stimulation interferes with spatial memory in the Morris water maze

O Buresova, E Panakhova, J Bures - Neuroscience letters, 1985 - Elsevier
Abstract Rats (n= 20) trained under monocular viewing conditions in the working memory
version of Morris water maze task received daily a single acquisition trial with a new location …

Functional hemidecortication by spreading depression or by focal epileptic discharge disrupts spatial memory in rats

E Panakhova, O Burešová, J Bureš - Behavioural processes, 1985 - Elsevier
The importance of neocortex for the acquisition and retrieval of the water tank navigation
task has been examined in 110 hooded rats. The animals were trained to swim to a small …