Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.
G Buchan, K Barrett, M Turner, D Chantry… - Clinical and …, 1988 - ncbi.nlm.nih.gov
In rheumatoid arthritis there is a chronic immune and inflammatory reaction which can lead
to the destruction of the diseased joint. Cytokine gene expression was studied in synovial …
to the destruction of the diseased joint. Cytokine gene expression was studied in synovial …
Tumour necrosis factor may contribute to the anaemia of malaria by causing dyserythropoiesis and erythrophagocytosis
IA Clark, G Chaudhri - British journal of haematology, 1988 - Wiley Online Library
Among the unexplained changes caused by malaria in several host species, including man
and mouse, are erythrophagocytosis and dyserythropoiesis. In order to see whether tumour …
and mouse, are erythrophagocytosis and dyserythropoiesis. In order to see whether tumour …
Glucocorticoids suppress the production of tumour necrosis factor by lipopolysaccharide-stimulated human monocytes.
We have investigated the modulating effect of steroids on the in vitro production of tumour
necrosis factor (TNF) by lipopolysaccharide (LPS)-stimulated human monocytes …
necrosis factor (TNF) by lipopolysaccharide (LPS)-stimulated human monocytes …
Newcastle disease virus as an antineoplastic agent: induction of tumor necrosis factor-α and augmentation of its cytotoxicity
RM Lorence, PA Rood, KW Kelley - JNCI: Journal of the …, 1988 - academic.oup.com
The oncolytic strain 73-T of Newcastle disease virus (NDV) has been reported to be
beneficial in the treatment of cancer patients, but little is known about its mechanism of …
beneficial in the treatment of cancer patients, but little is known about its mechanism of …
Circulating cytokines in patients with metastatic cancer treated with recombinant interleukin 2 and lymphokine-activated killer cells
BT Gemlo, MA Palladino Jr, HS Jaffe, TP Espevik… - Cancer research, 1988 - AACR
Abstract Treatment with recombinant interleukin 2 and lymphokine-activated killer cells (rIL-
2/LAK) has produced a clinical antitumor effect in preliminary human trials. The cytokines γ …
2/LAK) has produced a clinical antitumor effect in preliminary human trials. The cytokines γ …
Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
GE Ranges, A Zlotnik, T Espevik, CA Dinarello… - The Journal of …, 1988 - rupress.org
Recombinant murine (rm) TNF-alpha but not recombinant human (rh) TNF-alpha induces
the proliferation of murine thymocytes in the presence of a comitogenic stimulus. This effect …
the proliferation of murine thymocytes in the presence of a comitogenic stimulus. This effect …
In vivo administration of anti-CD3 prevents malignant progressor tumor growth
JDI Ellenhorn, R Hirsch, H Schreiber, JA Bluestone - Science, 1988 - science.org
Malignant progressor tumors are only weakly immunogenic and can evade host recognition
and rejection. One approach to therapy involves activation of the host antitumor cellular …
and rejection. One approach to therapy involves activation of the host antitumor cellular …
Up‐regulation of the expression of secretory component and HLA molecules in a human colonic cell line by tumour necrosis factor‐α and gamma interferon
D Kvale, P Brandtzaeg… - Scandinavian journal of …, 1988 - Wiley Online Library
Secretory component (SC) acts as receptor for polymeric IgA (pIgA) and pIgM on the
basolateral face of secretory epithelia. This study showed that both the production and …
basolateral face of secretory epithelia. This study showed that both the production and …
Tumor necrosis factor in malaria-induced abortion.
IA Clark, G Chaudhri - The American journal of tropical medicine …, 1988 - europepmc.org
The cause of fetal loss in malaria is not known. We report that a small (1.5-5.0 micrograms)
intravenous dose of recombinant human tumor necrosis factor (TNF) caused fetal death and …
intravenous dose of recombinant human tumor necrosis factor (TNF) caused fetal death and …
Characterization of the in Vitro and in Vivo Species Preference of Human and Murine Tumor Necrosis Factor-α
SM Kramer, BB Aggarwal, TE Eessalu, SM McCabe… - Cancer research, 1988 - AACR
The species preference of human and murine tumor necrosis factor-α (TNF-α) was
evaluated in human and murine systems for cytotoxic/cytostatic effects and receptor binding …
evaluated in human and murine systems for cytotoxic/cytostatic effects and receptor binding …