Abnormal vascularization of malignant tumors is associated with the development of
microregions of heterogeneous cells and environments. Experimental models such as …

In order to understand the role of glucose limitations in controlling multicellular tumor
spheroid growth, knowledge of the glucose diffusion coefficient is essential. The effective …

A method has been developed for metabolic imaging on a microscopic level in tumors,
tumor spheroids, and normal tissues. The technique makes it possible to determine the …

Detailed uptake kinetics by multicell spheroids of three tumor associated monoclonal
antibodies was investigated. The spheroids were established from a human melanoma cell …

Cells that have been grown as multicell tumor spheroids exhibit radioresistance compared
to the same cells grown in monolayers. Comparison of potentially lethal damage (PLD) …

Doxorubicin (DXR) has a positive inoculum effect and penetrates poorly into the core of
multicellular tumour spheroids (MTS). Cis-platin (DDP) displays neither of these …

• We compared the efficacy of cisplatin plus fluorouracil vs cisplatin plus cytarabine against
HEp-2 head and neck carcinoma cells in monolayer and multicellular tumor spheroid (MTS) …