The use of the Morris water maze in the study of memory and learning

R Brandeis, Y Brandys, S Yehuda - International Journal of …, 1989 - Taylor & Francis
Although the Morris Water Maze (MWM) was introduced only a few years ago, this technique
has gained wide popularity, as the large number of publications in which it is employed …

Differential effects of fornix and caudate nucleus lesions on two radial maze tasks: evidence for multiple memory systems

MG Packard, R Hirsh, NM White - Journal of Neuroscience, 1989 - Soc Neuroscience
The present experiments were designed to examine the hypothesis that the mammalian
brain contains anatomically distinct memory systems. Rats with bilateral lesions of caudate …

Configural association theory: The role of the hippocampal formation in learning, memory, and amnesia

RJ Sutherland, JW Rudy - Psychobiology, 1989 - Springer
It is proposed that the hippocampal formation makes a unique contribution to memory by
providing the neural basis for the initial acquisition and storage of configural associations …

Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge

BL Mcnaughton, CA Barnes, J Meltzer… - Experimental brain …, 1989 - Springer
The effects of massive destruction of granule cells of the fascia dentata on the spatial and
temporal firing characteristics of pyramidal cells in the CA1 and CA3 subfields of the …

The role of the fornix/fimbria and some related subcortical structures in place learning and memory

RJ Sutherland, AJ Rodriguez - Behavioural brain research, 1989 - Elsevier
Place learning and memory were assessed in rats with selective damage to the
fornix/fimbria or to subcortical structures which have a major connection with the …

The hippocampal formation is necessary for rats to learn and remember configural discriminations

JW Rudy, RJ Sutherland - Behavioural brain research, 1989 - Elsevier
A negative patterning discrimination problem was arranged by reinforcing rats for bar
pressing when either a light or tone was presented (L+/T+) but not reinforcing the response …

The effects of ibotenic acid lesions of the nucleus accumbens on spatial learning and extinction in the rat

LE Annett, A McGregor, TW Robbins - Behavioural brain research, 1989 - Elsevier
Rats with ibotenic acid lesions of the nucleus accumbens (N. Acc) were studied in two
spatial learning paradigms: a T-maze and a Morris water maze. Learning of a spatial …

Damage to the hippocampal formation in rats selectively impairs the ability to learn cue relationships

RJ Sutherland, RJ McDonald, CR Hill… - Behavioral and neural …, 1989 - Elsevier
We assessed the contribution of the hippocampal formation to performance in tasks that
require rats to respond to a relationship between discriminative stimuli. The first experiment …

Object exploration, habituation, and response to a spatial change in rats following septal or medial frontal cortical damage.

B Poucet - Behavioral neuroscience, 1989 - psycnet.apa.org
Normal rats and rats sustaining septal or medial frontal cortex lesions were compared in
experiments dealing with object exploration, habituation, and reaction to novelty (measured …

Inheritance of spatial learning ability in inbred mice: a classical genetic analysis.

M Upchurch, JM Wehner - Behavioral neuroscience, 1989 - psycnet.apa.org
The inheritance of spatial learning ability in inbred mice was examined by performance of a
classical genetic cross between the 2 inbred strains C57BL/6Ibg and DBA/2Ibg. The inbreds …