HLA-A-and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo …

NJ Stam, TM Vroom, PJ Peters… - International …, 1990 - academic.oup.com
The mAb HCA2 reacts preferentially with HLA-A locus heavy chains. Its reactivity contrasts
with that of HC1O, a mAb with more pronounced specificity for HLA-B and-C heavy chains …

Loss of MHC class‐I expression in cervical carcinomas

ME Connor, PL Stern - International journal of cancer, 1990 - Wiley Online Library
The expression of MHC class‐I antigens was analysed in 67 cervical carcinoma biopsies;
16% of the biopsies showed complete or heterogeneous loss of HLA expression as judged …

[PDF][PDF] Class I and class II major histocompatibility complex antigen expression on hepatocytes: a study in children with liver disease

A Lobo‐Yeo, G Senaldi, B Portmann, AP Mowat… - …, 1990 - Wiley Online Library
Controversy exists regarding major histocompatibility complex antigen expression on
hepatocytes. In this study, hepatocyte expression of class I and II major histocompatibility …

Clonal analysis of infiltrating T lymphocytes in liver tissue in viral hepatitis A.

B Fleischer, S Fleischer, K Maier, KH Wiedmann… - …, 1990 - ncbi.nlm.nih.gov
The pathogenic mechanism leading to liver tissue injury in hepatitis caused by hepatitis A
virus is unclear. We have randomly established T-cell clones from liver biopsies from four …

Lacking prognostic significance of β2-microglobulin, MHC class I and class II antigen expression in breast carcinomas

HO Wintzer, M Benzing, S Von Kleist - British journal of cancer, 1990 - nature.com
To evaluate the impact of MHC antigen expression on the survival of patients with cancer, 77
human breast carcinomas were investigated for the expression of beta 2-microglobulin (beta …

Selective and non-selective loss of immunoregulatory molecules (HLA-A, B, C antigens and LFA-3) in transitional cell carcinoma

AME Nouri, MEF Smith, D Crosby, RTD Oliver - British journal of cancer, 1990 - nature.com
The expression of the major histocompatibility complex (MHC) class I and II antigens and
lymphocyte function-associated antigen-3 (LFA-3) was investigated using …

Reduction of major histocompatibility complex class I antigens on invasive and high‐grade transitional cell carcinoma

Y Tomita, Y Matsumoto, T Nishiyama… - The Journal of …, 1990 - Wiley Online Library
We examined immunohistologically the expression of major histocompatibility complex
(MHC) class I and II antigens, which play important roles in immune reactions, on transitional …

Histocompatibility antigen expression in pulmonary carcinomas as indication of differentiation and of special subtypes

J Dämmrich, HK Müller‐Hermelink, A Mattner… - Cancer, 1990 - Wiley Online Library
In 70 human carcinomas of the lung the expression of histocompatibility antigens (HLA) was
investigated by using monoclonal antibodies in frozen sections. The immunoreactive tumor …

Expression of HLA ABC and DR antigens in thyroid neoplasia and correlation with mononuclear leukocyte infiltration

ME Fisfalen, WA Franklin, LJ DeGroot… - Journal of …, 1990 - Springer
The rejection of tumor cells by the immune system depends on the production of tumor-
associated antigens and the expression of HLA antigens on these cells. We therefore …

Production of monoclonal antibodies to squamous cell carcinoma antigens

JJ Quak, FJM Balm, JGP Brakkee… - … –Head & Neck …, 1990 - jamanetwork.com
• For therapeutic or diagnostic use of monoclonal antibodies in clinical oncology, high-
affinity IgG antibodies to tumorassociated antigens have to be generated. In order to find out …