The envelope glycoprotein complex of replication competent retroviruses is comprised of
two polypeptides, an external, glycosylated, hydrophilic polypeptide (SU) and a membrane …

Abstract In this paper Zeda Rosenberg and Anthony Fauci review the prevailing hypotheses
on the mechanisms by which human immunodeficiency virus (HIV) progressively and …

This report describes the structural characterization of the recombinant envelope
glycoprotein (rgp120) of human immunodeficiency virus type 1 produced by expression in …

ORGANELLE transport along microtubules is believed to be mediated by organelle-
associated force-generating molecules1. Two classes of microtubule-based organelle …

The CD4 antigen is the high affinity cellular receptor for the human immunodeficiency virus
type-1 (HIV-1). Binding of recombinant soluble CD4 (sCD4) or the purified V1 domain of …

IN the search for compounds active against human immunodeficiency virus (HIV), we have
found that members of a novel series of tetrahydro-imidazo [4, 5, 1-jk][l, 4]-benzodiazepin-2 …

RECENT advances in understanding the molecular basis of human X-linked muscular
dystrophies (for a review, see ref. 1) have come from the identification of dystrophin, a …

The binding of the CD4 receptor by the human immunodeficiency virus type 1 gp120 exterior
envelope glycoprotein is important for virus entry and cytopathic effect. To investigate the …

A human poliovirus receptor (PVR) gene was used to generate transgenic mice that express
PVR transcripts and poliovirus binding sites in a wide range of tissues. lntracerebral …

There is substantial evidence supporting the CD4 molecule as the principal cellular receptor
for the human immunodeficiency virus type 1 (HIV-1). A number of truncated recombinant …