A large body of evidence demonstrates that DNA methylation plays a role in gene regulation
in animal cells. Not only is there a correlation between gene transcription and …

The genes for over 100 restriction-modification systems have now been cloned, and
approximately one-half have been sequenced. Despite their similar function, they are …

We have studied the mechanism by which DNA methyiation inhibits transcription both in ceil-
free nuclear extracts and in the living ceil. Repression of transcription in vitro for four different …

Acute ethanol administration (3 g/kg twice a day) to pregnant mice, from the 9th thru the 11th
day of gestation, resulted in hypomethylation of fetal deoxyribonucleic acid (DNA). Nuclei …

The past decade has seen a dramatic increase in our understanding of early animal
development. The revised edition of this excellent book describes the results of this …

The tomato nuclear genome was determined to have a G+ C content of 37% which is among
the lowest reported for any plant species. Non-coding regions have a G+ C content even …

Codon usage is compared between four classes of species, with an emphasis on
characterization of low-usage codons. The classes of species analyzed include the …

Is it possible that fully differential cells, cells that have acquired specialized functions and
perhaps have lost some general properties can change their nature, becoming cells of …

DNA in differentiated somatic cells has a fixed pattern of methylation, which is faithfully
copied after replication. By contrast, the methylation patterns of many tissue-specific and …

What processes account for the remarkable variation in form and function that we see in the
living world and how might they be similar or different between microorganisms and …