Prenatal diagnosis with fetal cells isolated from maternal blood by multiparameter flow cytometry
JO Price, S Elias, SS Wachtel, K Klinger… - American journal of …, 1991 - Elsevier
A long-sought goal of medical genetics has been development of prenatal diagnostic
procedures that do not endanger the conceptus. Reliable and universal screening for …
procedures that do not endanger the conceptus. Reliable and universal screening for …
Fetal cells in the maternal circulation: isolation by multiparameter flow cytometry and confirmation by polymerase chain reaction
S Wachtel, S Elias, J Price, G Wachtel… - Human …, 1991 - academic.oup.com
During pregnancy, nucleated fetal erythrocytes enter the maternal circulation and can be
isolated efficiently from the maternal cells by multiparameter flow cytometry. Male DNA …
isolated efficiently from the maternal cells by multiparameter flow cytometry. Male DNA …
Trophoblast‐like cells sorted from peripheral maternal blood using flow cytometry: a multiparametric study involving transmission electron microscopy and fetal DNA …
JF Bruch, P Metezeau… - Prenatal …, 1991 - Wiley Online Library
Three monoclonal antibodies (MAbs) against trophoblast (GB17, GB21, and GB25) and flow
cytometry were used to sort trophoblast‐like cells (TLCs) from peripheral blood of pregnant …
cytometry were used to sort trophoblast‐like cells (TLCs) from peripheral blood of pregnant …
Detection of fetal cells in maternal blood
SC Yeoh, IL Sargent, CWG Redman… - Prenatal …, 1991 - Wiley Online Library
We report the detection of fetal cells in the maternal circulation by enzymatic amplification of
a single copy gene sequence that was fetal‐specific. Fetal HLA‐A2‐positive cells were …
a single copy gene sequence that was fetal‐specific. Fetal HLA‐A2‐positive cells were …
Absence of fetal cells in maternal circulation at a level of 1 in 25,000
Y Nakagome, S Seki, S Nagafuchi… - American journal of …, 1991 - Wiley Online Library
A dual polymerase chain reaction (PCR) technique is developed which enables the
detection of one part male DNA in 25,000 parts female DNA. The technique amplifies a part …
detection of one part male DNA in 25,000 parts female DNA. The technique amplifies a part …
[引用][C] On a non‐invasive approach to prenatal diagnosis based on the detection of fetal nucleated cells in maternal blood samples
M Adinolfi - Prenatal diagnosis, 1991 - Wiley Online Library
Following the introduction of the polymerase chain reaction (PCR) method for the
amplification of specific DNA sequences using a single or a small number of cells (Saiki et …
amplification of specific DNA sequences using a single or a small number of cells (Saiki et …