Reactive oxygen and ischemia/reperfusion injury of the liver

H Jaeschke - Chemico-biological interactions, 1991 - Elsevier
Pharmacological experiments suggested that reactive oxygen species contribute to
ischemia-reperfusion injury of the liver. Since there is no evidence that quantitatively …

Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia

H Jaeschke, AP Bautista, Z Spolarics… - Free radical research …, 1991 - Taylor & Francis
The objective of this study was to identify the cellular source of the vascular oxidant stress in
hepatic ischemia-reperfusion injury in male Fischer rats. Nonparenchymal cells (Kupffer …

Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism

H Jaeschke, A Farhood… - American Journal of …, 1991 - journals.physiology.org
To investigate the role of neutrophils (PMNs) and PMN-dependent adhesion molecules in
the pathogenesis of liver injury in a model of endotoxin shock, male ICR mice received a …

Reperfusion injury: a role for neutrophils

JJ Lemasters, RG Thurman - Hepatology, 1991 - journals.lww.com
To determine the role of neutrophils in the pathogenesis of hepatic ischemia/reperfusion
injury, livers from male Fischer rats were subjected to 45 min of no-flow ischemia followed by …