In Parkinson's disease (PD), in addition to degeneration of the nigrostriatal dopaminergic
pathway, a variety of neuronal systems are involved, causing multiple neuromediator …

Quantitative autoradiographic analysis of serotonin 5-HT 1A receptors in the human brain,
using [3 H] 8-OH-DPAT as a ligand, reveals region-specific decreases in receptor labeling …

The density of 5-HT 1A binding using 3 H-8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-
DPAT) as binding ligand, was studied in human frontal cortex of suicide victims and normal …

The binding of the selective 5-HT 2 antagonist [3 H] ketanserin has been investigated in the
temporal cortex of patients with Alzheimer's disease (SDAT), Parkinson's disease (PD) …

Abstract Serotonin (5-hydroxytryptamine; 5HT) uptake sites have been measured using the
selective high affinity uptake inhibitor 3 H-citalopram in post-mortem frontal cortex from …

Decreased cerebrospinal fluid (CSF), somatostatinlike immunoreactivity (SLI) and
alterations in the CSF monamine metabolites 3-methoxy-4-hydroxyphenylethylglycol …

The regional distribution of [3 H] idazoxan and [3 H] rauwolscine was studied
autoradiographically in human brain.[3 H] Idazoxan binds with high affinity to α 2 …

The topography of β-adrenergic receptors in the rat and human hippocampal formation was
assessed by in vitro binding of 125 I-pindolol to tissue sections. Marked differences were …

The high-affinity binding of the β-adrenergic receptor antagonist,[3 H] dihydroalprenolol, was
measured in homogenates of frontal cortex (Brodmann's areas 8 and 9) of suicide victims …

Changes in indices postulated to reflect central serotonergic mechanisms have been desc~
bed in both suicide victims and suicide attempters (Asberg et al 1987; Deakin 1989; Mann et …