A novel mechanism for regulating dopamine activity in subcortical sites and its possible
relevance to schizophrenia is proposed. This hypothesis is based on the regulation of …

During most of the first half of this century psychologists knew what they wanted to do but
had no idea how to do it, and during the second half they have, for the most part, been so …

In the present study, the role of dopaminergic mechanisms within different striatal
subregions in feeding behavior was examined in food-deprived (19 h) rats. Specifically, the …

Hungry rats were exposed to a conditioned stimulus (CS) event (either light onset or offset)
before food delivery. After several weeks of contingent CS+/food pairings, animals were …

Rats were presented for 1 h with 0.7%, 7% or 34% sucrose solutions, either separately with
water as an alternative (two-bottle test), or with all three concentrations concurrently …

Rats were implanted with bilateral indwelling cannulae, in the nucleus accumbens (NAS),
anterodorsal striatum (ADS) or basolateral amygdala (BLA). Administration of sulpiride to the …

Rats performed on two multiple random-interval schedules, in which sequences of
ascending or descending reinforcement densities were balanced between the schedules …

Two experiments investigated the effects of haloperidol (0.1 mg/kg) on the partial
reinforcement extinction effect (PREE). In experiment 1 two groups of rats were trained to run …

Reinforced responding of 17-day-old rat pups was assessed after blockade of dopamine D1
and D2 receptor systems. Rat pups were trained to traverse a straight alley for nipple …

Three motor-impairing drugs with different putative mechanisms of action (haloperidol 0.00,
0.075, 0.15, 0.30 mg/kg IP; pentobarbital 0.00, 4.5, 9, 12 mg/kg IP; and dantrolene 0.00, 5 …