Decoding calcium signals by multifunctional CaM kinase

H Schulman, PI Hanson, T Meyer - Cell Calcium, 1992 - Elsevier
Multifunctional Ca 2+ calmodulin-dependent protein kinase (CaM kinase) is one of the three
major protein kinases coordinating cellular responses to hormones and neurotransmitters. It …

Calcium-regulated phosphorylation within the leucine zipper of C/EBPβ

M Wegner, Z Cao, MG Rosenfeld - Science, 1992 - science.org
Alterations in intracellular calcium levels activate several signal transduction pathways
resulting in distinct patterns of gene expression. Here, a pathway for calcium-mediated …

[HTML][HTML] Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis.

PI Hanson, H Schulman - Journal of Biological Chemistry, 1992 - Elsevier
Initial autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase
(CaM kinase) occurs at Thr286 (the “autonomy” site) and converts the kinase from a Ca (2+) …

Contrasting patterns in the localization of glutamic acid decarboxylase and Ca2+/calmodulin protein kinase gene expression in the rat centrat nervous system

DL Benson, PJ Isackson, CM Gall, EG Jones - Neuroscience, 1992 - Elsevier
The expression of the genes encoding the alpha subunit of type II calcium calmodulin-
dependent protein kinase (CaM II kinase α) and the 67,000 mol. wt form of glutamic acid …

Regulation and role of brain calcium/calmodulin-dependent protein kinase II

RJ Colbran - Neurochemistry international, 1992 - Elsevier
Abstract Ca 2+/calmodulin-dependent protein kinase II (CaMKII) exhibits a broad substrate
specificity and regulates diverse responses to physiological changes of intracellular Ca 2+ …

Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal CA1 neurons

SA Mackler, BP Brooks, JH Eberwine - Neuron, 1992 - cell.com
The molecular effects of use-dependent changes in synapti---c transmission were studied in
individual CA1 pyramidal neurons from rat hippocampal slices. Potentiation of excitatory …

Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2.

MD Planas‐Silva, AR Means - The EMBO Journal, 1992 - embopress.org
Calcium/calmodulin dependent protein kinase II (CaMKII) is a multifunctional
serine/threonine protein kinase. We have created a calcium/calmodulin independent form of …

Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase.

FH Cruzalegui, MS Kapiloff, JP Morfin… - Proceedings of the …, 1992 - National Acad Sciences
A regulatory region involved in both autoinhibition and calmodulin (CaM) binding has
previously been identified in the multifunctional Ca2+/CaM-dependent protein kinase (CaM …

Structure, Expression, and Chromosome Location of the Gene for the β Subunit of Brain-Specific Ca2+/Calmodulin- Dependent Protein Kinase II Identified by …

U Karls, U Müller, DJ Gilbert, NG Copeland… - … and cellular biology, 1992 - Taylor & Francis
The transgenic mouse strain CAT40 carries in its germ line one copy of a DNA construct
consisting of the chloramphenicol acetyltransferase gene and the immunoglobulin heavy …

Multiple forms and distribution of calcium/calmodulin‐stimulated protein kinase II in brain

JAP Rostas, PR Dunkley - Journal of neurochemistry, 1992 - Wiley Online Library
In recent years, the enzyme Ca2+/calmodulin‐stimulated protein kinase II1 (CaM‐PK II) as
attracted a great deal of interest. CaM‐PK II is the most abundant calmodulin‐stimulated …