Apolipoproteins B, CIII, and AII are synthesized primarily in the liver and intestine and play
an important role in lipid and cholesterol metabolism. It was previously shown that the cis …

The liver is where a large number of metabolic regulatory processes take place. Here, a set
of enzymes are constitutively expressed or induced whose function is to metabolize the …

Epidemiological studies have demonstrated that the risk of coronary artery disease (CAD) is
increased in smokers but reduced in individuals with elevated plasma levels of high density …

Mutations in gene promoter/regulatory regions represent an important class of lesion
causing human genetic disease. Such mutations are associated with either increases or …

We investigated a common polymorphism in the human apolipoprotein AI gene promoter at
a position 76 bp upstream of the transcriptional start site. 54 human subjects, whose apoAI …

In human, the gene coding for apolipoprotein AI (apo AI), a protein of the plasma lipid
transport system, is expressed only in the liver and the intestine. A naturally occurring A to G …

The human apolipoprotein B (apoB) promoter region (-150 to+ 124) is transcriptionally
active in HepG2 and CaCo-2 but not in HeLa cells. In the present study, we demonstrate that …

Glucocorticoid hormones increase high-density lipoprotein (HDL) levels in vivo. However,
there is little known about the mechanism by which glucocorticoids alter HDL metabolism …

The genes coding for apolipoproteins B and AI (apoB and apoA-I) are potential candidate
loci for studying heritable determinants of lipid levels, a primary risk factor for development of …