Dendritic cells: antigen presentation, accessory function and clinical relevance

RM Steinman, M Witmer-Pack, K Inaba - Dendritic cells in fundamental and …, 1993 - Springer
Laboratories around the world, many represented here, have now elucidated the broad
outlines of the dendritic cell system. Dendritic cells occupy three compartments: a) …

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

FO Nestle, XG Zheng, CB Thompson… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
The relative contribution of dermal-derived immunocompetent cells to the overall
immunologic response in skin has been hampered by the lack of appropriate isolation …

Evidence for a Clonal Origin of Methicillin Resistance in Staphylococcus aureus

B Kreiswirth, J Kornblum, RD Arbeit, W Eisner… - Science, 1993 - science.org
Soon after methicillin was introduced into clinical practice in the early 1960s, resistant
strains of Staphylococcus aureus (MRSA) appeared, bearing a newly acquired resistance …

Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo.

K Inaba, M Inaba, M Naito, RM Steinman - The Journal of experimental …, 1993 - rupress.org
Dendritic cells, while effective in sensitizing T cells to several different antigens, show little or
no phagocytic activity. To the extent that endocytosis is required for antigen processing and …

Phagocytosis of antigens by Langerhans cells in vitro.

C Reis e Sousa, PD Stahl, JM Austyn - The Journal of experimental …, 1993 - rupress.org
Dendritic cells (DC) isolated from lymphoid tissues are generally thought to be
nonphagocytic in culture. It has therefore been unclear how these cells could acquire …

Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen‐specific T cells

H Moll, H Fuchs, C Blank… - European journal of …, 1993 - Wiley Online Library
Murine epidermal Langerhans cells (LC) have been shown to internalize Leishmania major,
a cause of human cutaneous leishmaniasis, and to stimulate a vigorous parasite‐specific T …

Differential effect of IL-10 on dendritic cell-induced T cell proliferation and IFN-gamma production.

SE Macatonia, TM Doherty, SC Knight… - Journal of immunology …, 1993 - journals.aai.org
IL-10 has previously been shown to inhibit cytokine production by Th1 cells by blocking
macrophage accessory cell function. In this study we demonstrate that dendritic cell-induced …

Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo.

LM Liu, GG MacPherson - The Journal of experimental medicine, 1993 - rupress.org
In the rat, mesenteric lymphadenectomy allows collection of dendritic cells (DC) derived from
the small intestine after cannulation of the thoracic duct. We prepared rats this way and …

B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes.

F Ronchese, B Hausmann - The Journal of experimental medicine, 1993 - rupress.org
The ability of B cells or macrophages and dendritic cells (DC) to elicit class II-restricted T cell
responses in vivo was compared using a mouse chimera model. Severe combined …

Role of dendritic cells in the priming of CD4+ T lymphocytes to peptide antigen in vivo.

D Levin, S Constant, T Pasqualini, R Flavell… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
The contribution of dendritic cells (DC) in the initial priming of CD4+ T lymphocytes in vivo
was examined. To assess the capacity of different APC to prime CD4+ T cells, a series of …