Thioxo quinoline compounds, composition and method of use
PAR Bruneau - US Patent 5,240,941, 1993 - Google Patents
The invention concerns a thioxo heterocycle of the formula I pr' I Q-A1-Xi-Ar-c-R2 wherein Q
is a 10-membered bicyclic heterocyclic moi ety containing 1 or 2 N's which bears 1 or 2 …
is a 10-membered bicyclic heterocyclic moi ety containing 1 or 2 N's which bears 1 or 2 …
Quinoline ether alkanoic acids
R Zamboni, P Prasit, RN Young - US Patent 5,232,916, 1993 - Google Patents
Compounds having the formula:< IMAGE> I are inhibitors of leukotriene biosynthesis. These
compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective …
compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective …
5-lipoxygenase inhibitors quinoline or isoquinoline derivatives
GC Crawley, PN Edwards - US Patent 5,221,677, 1993 - Google Patents
Q is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic
moiety con taining one or two nitrogen atoms; X is oxy, thio, sulphinyl, sulphonyl or imino; Ar …
moiety con taining one or two nitrogen atoms; X is oxy, thio, sulphinyl, sulphonyl or imino; Ar …
Diaryl ether hetrocycles
TGC Bird, PN Edwards - US Patent 5,208,259, 1993 - Google Patents
Ari is optionally substituted phenyl or naphthyl; X is oxy, thio, sulphinyl or sulphonyl; Ar2 is
optionally substituted phenylene, or a 6-mem bered heterocyclene moiety containing up to …
optionally substituted phenylene, or a 6-mem bered heterocyclene moiety containing up to …
Bicyclic heterocyclic derivatives as 5-lipoxygenase inhibitors
PAR Bruneau, GC Crawley, K Oldham - US Patent 5,179,115, 1993 - Google Patents
Q-A1-X-Ar-c-R2 wherein Q is an optionally substituted 9-membered bicyclic heterocyclic
moiety containing 1 or 2 N's and optionally a further N, O or S heteroatom; Al is a direct link …
moiety containing 1 or 2 N's and optionally a further N, O or S heteroatom; Al is a direct link …
Substituted-optionally hydrogenated isoquinoline compounds, pharmaceutical compositions and pharmaceutical method of use
TGC Bird - US Patent 5,217,978, 1993 - Google Patents
US5217978A - Substituted-optionally hydrogenated isoquinoline compounds,
pharmaceutical compositions and pharmaceutical method of use - Google Patents …
pharmaceutical compositions and pharmaceutical method of use - Google Patents …
Benzoxazine derivatives as inhibitors of leukotrienes
PAR Bruneau, GC Crawley - US Patent 5,217,969, 1993 - Google Patents
Q-Al-Xl-Ar-C-R2 wherein Q is an optionally substituted 10-membered bicyclic heterocyclic
moiety containing 1 or 2 N's and a further O or S heteroatom; A1 is a direct link to X1 or (1 …
moiety containing 1 or 2 N's and a further O or S heteroatom; A1 is a direct link to X1 or (1 …
1, 6-naphthyridone derivatives having angiotensin ii antagonist activity
AH Ratcliffe, RJ Pearce, KH Gibson, R Wood… - US Patent …, 1993 - Google Patents
The invention concerns pharmaceutically useful com pounds of the formula I, in which R, R2,
R3, R “, Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic …
R3, R “, Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic …
Quinoxalinyl derivatives suitable for use in leukotriene mediated disease
GC Crawley, PN Edwards, JMMM Girodeau - US Patent 5,236,919, 1993 - Google Patents
QAX-Ar-C-R2 wherein Q is an optionally substituted 6-membered monocyclic or 10-
membered bicyclic heterocyclic moi ety containing one or two nitrogen atoms; A is (1-6C) …
membered bicyclic heterocyclic moi ety containing one or two nitrogen atoms; A is (1-6C) …
Aryl derivatives
RI Dowell, PN Edwards, K Oldham - US Patent 5,225,438, 1993 - Google Patents
US5225438A - Aryl derivatives - Google Patents US5225438A - Aryl derivatives - Google Patents
Aryl derivatives Download PDF Info Publication number US5225438A US5225438A …
Aryl derivatives Download PDF Info Publication number US5225438A US5225438A …