Non-invasive prenatal diagnosis using fetal cells in maternal blood.
YM Lo - Journal of clinical pathology, 1994 - ncbi.nlm.nih.gov
Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford OX3 9DU YM D Lo
Correspondence to: Dr YM D Lo Accepted for publication 31 August 1994 Historical …
Correspondence to: Dr YM D Lo Accepted for publication 31 August 1994 Historical …
Isolating fetal cells in maternal circulation for prenatal diagnosis
JL Simpson, S Elias - Prenatal Diagnosis, 1994 - Wiley Online Library
Fetal cells unequivocally exist in and can be isolated from maternal blood. Erythroblasts,
trophoblasts, granulocytes and lymphocytes have all been isolated by various density …
trophoblasts, granulocytes and lymphocytes have all been isolated by various density …
Detection of fetal RhD sequence from peripheral blood of sensitized RhD‐negative pregnant women
YMD Lo, L Noakes, PJ Bowell… - British Journal of …, 1994 - Wiley Online Library
A sensitive PCR‐based assay was developed to amplify fetal‐derived rhesus D (RhD)
sequence from peripheral blood of RhD‐negative pregnant women with circulating anti‐D …
sequence from peripheral blood of RhD‐negative pregnant women with circulating anti‐D …
Prenatal determination of fetal rhesus D status by DNA amplification of peripheral blood of rhesus-negative mothers.
YM Lo, PJ Bowell, M Selinger, IZ Mackenzie… - Annals of the New …, 1994 - europepmc.org
We have developed a sensitive PCR-based assay for the RhD gene and used it to detect
circulating fetal cells from RhD-positive fetuses from peripheral blood of RhD-negative …
circulating fetal cells from RhD-positive fetuses from peripheral blood of RhD-negative …
Fetal nucleated cells in maternal peripheral blood after delivery
H Hamada, T Arinami, H Hamaguchi, T Kubo - American journal of …, 1994 - Elsevier
OBJECTIVE: The purpose of this study was to determine the frequency of fetal nucleated
cells and their serial changes in maternal peripheral blood after delivery. STUDY DESIGN: A …
cells and their serial changes in maternal peripheral blood after delivery. STUDY DESIGN: A …
Clinical trials and experience: Boston.
DW Bianchi - Annals of the New York Academy of Sciences, 1994 - europepmc.org
Our cumulative experience continues to validate the fetal nucleated erythrocyte as the target
fetal cell type of choice, primarily because it reflects the cytogenetic status of the current …
fetal cell type of choice, primarily because it reflects the cytogenetic status of the current …
Improved detection of fetal cells from maternal blood with polymerase chain reaction
LR Adkison, RH Andrews, NL Vowell… - American journal of …, 1994 - Elsevier
OBJECTIVE: The objective was to test the reliability of new deoxyribonucleic acid primers
that have previously been used very efficiently by this laboratory with amniolysate samples …
that have previously been used very efficiently by this laboratory with amniolysate samples …
Screening of monoclonal antibodies recognizing oncofetal antigens for isolation of trophoblasts from maternal blood for prenatal diagnosis
LG Durrant, KM McDowell, RA Holmes… - Prenatal …, 1994 - Wiley Online Library
Many monoclonal antibodies have been produced against tumour‐associated cell surface
antigens for cancer therapy. They have therefore been selected for minimal reactivity with …
antigens for cancer therapy. They have therefore been selected for minimal reactivity with …
FISH: sensitivity and specificity on sorted and unsorted cells.
KW Klinger - Annals of the New York Academy of Sciences, 1994 - europepmc.org
The results of our FISH studies of maternal samples and model systems are very
encouraging. Aneuploidies have been detected prospectively, and the model experiments …
encouraging. Aneuploidies have been detected prospectively, and the model experiments …
ISH and PCR study with Y-specific probe/primers.
AM Björkqvist, M Wessman, M Vuorinen… - Annals of the New …, 1994 - europepmc.org
Our main aim was to evaluate whether maternal whole venous blood could be used for
determination of fetal sex, when no enrichment of fetal cells was attempted and when" …
determination of fetal sex, when no enrichment of fetal cells was attempted and when" …