Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

R Bourtchuladze, B Frenguelli, J Blendy, D Cioffi… - Cell, 1994 - cell.com
The cAMP-responsive element-binding protein (WEB) has been implicated in the activation
of protein synthesis required for long-term facilitation, a cellular model of memory in Aplysia …

Parallel information processing in the water maze: evidence for independent memory systems involving dorsal striatum and hippocampus

RJ McDonald, NM White - Behavioral and neural biology, 1994 - Elsevier
This experiment investigated the ability of rats withdorsal striatal or fornix damage to learn
the location of a visible platform in a water maze. We also assessed the animals' ability to …

Targeting learning

SGN Grant, AJ Silva - Trends in neurosciences, 1994 - cell.com
Novel transgenic approaches provide an exciting opportun@ to assess the impact of the
loss of specific genes in the biochemistry and electrophysiology of neurons involved in a …

Amygdala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes.

MG Packard, L Cahill… - Proceedings of the …, 1994 - National Acad Sciences
These experiments investigated the effects, on memory, of injections of d-amphetamine (10
micrograms/0.5 microliter) administered into the amygdala, hippocampus, or caudate …

Spatial information content and reliability of hippocampal CA1 neurons: effects of visual input

EJ Markus, CA Barnes, BL McNaughton… - …, 1994 - Wiley Online Library
The effects of darkness on quantitative spatial firing characteristics of 235 hippocampal CA1
“complex spike”(CS) cells were studied in young and old Fischer‐344 rats during food …

A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: evidence for behavioural flexibility, but not for impaired spatial …

JPC de Bruin, F Sanchez-Santed, RPW Heinsbroek… - Brain research, 1994 - Elsevier
In this study, the functional properties of the medial prefrontal cortex (mPFC) of the rat were
examined in a task for spatial navigation. The dorsomedial (dmPFC) and ventromedial …

Anterograde and retrograde tracing of projections from the ventral tegmental area to the hippocampal formation in the rat

A Gasbarri, MG Packard, E Campana, C Pacitti - Brain research bulletin, 1994 - Elsevier
Employing anterograde tracing with Phaseolus vulgaris-leucoagglutinin (PHA-L), and a
triple labeling protocol using retrogradely transported fluorescent tracers, we examined the …

Ontogeny of contextual fear conditioning in rats: implications for consolidation, infantile amnesia, and hippocampal system function.

JW Rudy, P Morledge - Behavioral neuroscience, 1994 - psycnet.apa.org
The authors present developmental evidence that contextual fear conditioning is supported
by a short-term memory system that supports conditioning immediately after a shock and by …

DBA/2 and C57BL/6 mice differ in contextual fear but not auditory fear conditioning.

R Paylor, R Tracy, J Wehner, JW Rudy - Behavioral neuroscience, 1994 - psycnet.apa.org
It has been proposed that DBA/2 and C57BL/6 mice perform differently on some learning
and memory tasks because of functional differences in the hippocampal formation. To …

The behavioral neurobiology of learning and memory: a conceptual reorientation

CH Vanderwolf, DP Cain - Brain Research Reviews, 1994 - Elsevier
Research on the neurobiology of learning and memory has been guided by two major
theories:(i) memory as a psychological process and (ii) memory as a change in synaptic …