Tat-mediated delivery of heterologous proteins into cells.
S Fawell, J Seery, Y Daikh, C Moore… - Proceedings of the …, 1994 - National Acad Sciences
The Tat protein of human immunodeficiency virus 1 (HIV-1) can enter cells efficiently when
added exogenously in tissue culture. To assess if Tat can carry other molecules into cells …
added exogenously in tissue culture. To assess if Tat can carry other molecules into cells …
[HTML][HTML] Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis.
Folic acid was covalently conjugated to 66-nm liposomes via spacers of various lengths in
an attempt to target the liposomes to KB cells expressing folate receptors. Spacers of short …
an attempt to target the liposomes to KB cells expressing folate receptors. Spacers of short …
Selective targeting of malignant cells with cytotoxin-folate conjugates
Previous work has shown that proteins can be nondestructively delivered into the cytoplasm
of folate receptor-bearing cells if the proteins are conjugated to folic acid prior to addition to …
of folate receptor-bearing cells if the proteins are conjugated to folic acid prior to addition to …
Inhibition of leukaemia cell proliferation by folic acid–polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells
G Citro, C Szczylik, P Ginobbi, G Zupi… - British journal of …, 1994 - nature.com
The inhibitory effect of c-myb antisense oligodeoxynucleotides (ODNs) conjugated to folic
acid (FA) on HL-60 cell proliferation was examined. Folic acid was covalently linked to a …
acid (FA) on HL-60 cell proliferation was examined. Folic acid was covalently linked to a …
Gene therapy for phenylketonuria
RC Eisensmith, SLC Woo - Acta Paediatrica, 1994 - Wiley Online Library
Classical phenylketonuria (PKU) is an autosomal recessive disorder caused by a deficiency
of hepatic phenylalanine hydroxylase (PAH). Three different vector systems have been …
of hepatic phenylalanine hydroxylase (PAH). Three different vector systems have been …
Homeodomain proteins in development and therapy
A Dorn, M Affolter, WJ Gehring, W Leupin - Pharmacology & therapeutics, 1994 - Elsevier
Homeobox genes encode transcriptional regulators found in all organisms ranging from
yeast to humans. In Drosophila, a specific class of homeobox genes, the homeotic genes …
yeast to humans. In Drosophila, a specific class of homeobox genes, the homeotic genes …
Lactose-carrying polystyrene as a drug carrier: investigation of body distributions to parenchymal liver cells using 125I-labelled lactose-carrying polystyrene
M Goto, H Yura, CW Chang, A Kobayashi… - Advances in Drug …, 1994 - Elsevier
Directed toward pharmacological applications of lactose-carrying polystyrene,(poly (Np-
vinylbenzyl-O-β-D-galactopyranosyl-(l→ 4)-D-gluconamide), PVLA), its body distribution …
vinylbenzyl-O-β-D-galactopyranosyl-(l→ 4)-D-gluconamide), PVLA), its body distribution …
Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by antisense oligonucleotide treatment.
U Steinhoff, U Zügel… - Proceedings of the …, 1994 - National Acad Sciences
T lymphocytes with specificity for the bacterial heat shock protein (hsp) 60 recognize
stressed host cells, thus possibly promoting pathogenesis of certain infectious and …
stressed host cells, thus possibly promoting pathogenesis of certain infectious and …
Chemical modification of ligands for cell receptors to introduce foreign compounds into the cells
G Citro, P Ginobbi, A Candiloro, A Milani… - Diseases of the colon & …, 1994 - journals.lww.com
PURPOSE: In all forms of drug therapy, clinicians must ensure that the maximum therapeutic
benefit is achieved without inducing unacceptable toxicity. An improvement in the …
benefit is achieved without inducing unacceptable toxicity. An improvement in the …
[图书][B] Pharmaceutical design and development: a molecular biology approach
TV Ramabhadran - 1994 - books.google.com
Page 1 ELLIS HORWOOD SERIES IN PHARMACEUTICAL TECHNOLOGY
HARMACEUTICAL DESIGN AND a molecular biology approach Also available as a printed …
HARMACEUTICAL DESIGN AND a molecular biology approach Also available as a printed …