Increased CNTF gene expression in process‐bearing astrocytes following injury is augmented by R (−)‐deprenyl

NA Seniuk, JT Henderson, WG Tatton… - Journal of …, 1994 - Wiley Online Library
Clinical trials have demonstrated that R (-)-deprenyl delays the need for levodopa treatment
in Parkinson's disease (Parkinson Study Group, 1993) and slows the progression of some …

Analysis of the functional effects of a mutation in SOD1 associated with familial amyotrophic lateral sclerosis

T Tsuda, S Munthasser, PE Fraser, ME Percy, I Rainero… - Neuron, 1994 - cell.com
Summary Mutations in the Cu, Zn superoxide dismutase (SODI) gene have been reported in
some pedigrees with Familial Amyotrophic lateral Sclerosis (FALS). We have investigated …

(–)‐Deprenyl alters the survival of adult murine facial motoneurons after axotomy: increases in vulnerable C57BL strain but decreases in motor neuron degeneration …

C Oh, B Murray, N Bhattacharya… - Journal of …, 1994 - Wiley Online Library
Abstract The effect of (–)‐deprenyl on the survival of axotomized adult murine facial
motoneurons was investigated. Previously,(—)‐deprenyl was shown to increase the number …

(+) MK-801 prevents the DDC-induced enhancement of MPTP toxicity in mice

F Vaglini, F Fascetti, F Fornai, R Maggio, GU Corsini - Brain research, 1994 - Elsevier
In order to reach deeper insight into the mechanism of diethyldithiocarbamate (DDC)-
induced enhancement of MPTP toxicity in mice, MK-801, a non-competitive antagonist of …

Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

JK Andersen, DM Frim, O Isacson, MF Beal… - Brain research, 1994 - Elsevier
To examine whether expressing high levels of monoamine oxidase (MAO-B) activity
abberently in neurons results in increased sensitivity of dopaminergic neurons to the …

Noradrenergic control of gap junction permeability in cultured striatal astrocytes

C Giaume, M Briley, M Marien - Noradrenergic Mechanisms in …, 1994 - books.google.com
Although it has been well documented that glial cells constitute the major cell population in
the mammalian brain (Pope, 1978; Kimelberg and Norenberg, 1989), for many years most of …

Recovery from MPTP-induced parkinsonian manifestations following locus coeruleus lesions in squirrel monkeys

M Mavridis, AD Degryse, AJ Lategan… - Noradrenergic …, 1994 - books.google.com
Idiopathic Parkinson's disease is a non-hereditary, progressive neurological disorder
affecting equally both sexes, usually from the sixth decade of life onward (Hoehn and Yahr …