The endocytic activity of dendritic cells.
RM Steinman, J Swanson - The Journal of experimental medicine, 1995 - ncbi.nlm.nih.gov
I n this issue, Sallusto et al.(1) report that dendritic cells. can vigorously internalize solutes by
macropinocytosis, delivering these to MHC class II-rich vesicles (MIIVs). In the most familiar …
macropinocytosis, delivering these to MHC class II-rich vesicles (MIIVs). In the most familiar …
Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment …
F Sallusto, M Cella, C Danieli… - The Journal of …, 1995 - rupress.org
We have previously demonstrated that human peripheral blood low density mononuclear
cells cultured in granulocyte/macrophage colony-stimulating factor (GM-CSF) and …
cells cultured in granulocyte/macrophage colony-stimulating factor (GM-CSF) and …
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.
SE Macatonia, NA Hosken, M Litton… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Dendritic cells are APCs that are unique in their potency to stimulate proliferation of primary
Ag-specific responses in vitro and in vivo. In this study, we demonstrate that dendritic cells …
Ag-specific responses in vitro and in vivo. In this study, we demonstrate that dendritic cells …
Gene transfer as cancer therapy
G Dranoff, RC Mulligan - Advances in immunology, 1995 - Elsevier
The development of recombinant DNA technologies has generated remarkable insight into
the mechanisms underlying carcinogenesis. The recognition that specific mutations in …
the mechanisms underlying carcinogenesis. The recognition that specific mutations in …
Engagement of CD27 with its ligand CD70 provides a second signal for T cell activation.
RQ Hintzen, SM Lens, K Lammers… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Molecules of the TNF-R family have been shown to be essential in the regulation of
lymphocyte growth and differentiation. The TNF-R family member CD27 binds to a type II …
lymphocyte growth and differentiation. The TNF-R family member CD27 binds to a type II …
Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes.
A Porgador, E Gilboa - The Journal of experimental medicine, 1995 - rupress.org
It has previously been shown that bone marrow-generated dendritic cells (DC) are potent
stimulators in allogeneic mixed leukocyte reactions and are capable of activating naive …
stimulators in allogeneic mixed leukocyte reactions and are capable of activating naive …
Glucocorticoids down‐regulate dendritic cell function in vitro and in vivo
M Moser, T De Smedt, T Sornasse… - European journal of …, 1995 - Wiley Online Library
Exogenous glucocorticoid hormones are widely used as therapeutical agents, whereas
endogenous glucocorticoids may act as physiological immunosuppressants involved in the …
endogenous glucocorticoids may act as physiological immunosuppressants involved in the …
[HTML][HTML] A distinct pattern of cytokine gene expression by human CD83+ blood dendritic cells
LJ Zhou, TF Tedder - Blood, 1995 - Elsevier
Dendritic cells are the most potent antigen-presenting cells of the immune system. Although
dendritic cells are likely to secrete selective cytokines that facilitate antigen presentation, the …
dendritic cells are likely to secrete selective cytokines that facilitate antigen presentation, the …
Infection frequency of dendritic cells and CD4+ T lymphocytes in spleens of human immunodeficiency virus-positive patients
D McIlroy, B Autran, R Cheynier… - Journal of …, 1995 - Am Soc Microbiol
Dendritic cells (DC) are specialized antigen-presenting leukocytes that are responsible for
the activation of naive as well as memory T lymphocytes. If infected by human …
the activation of naive as well as memory T lymphocytes. If infected by human …
Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells.
HW Nijman, MJ Kleijmeer, MA Ossevoort… - The Journal of …, 1995 - rupress.org
Dendritic cells (DC) represent potent antigen-presenting cells for the induction of T cell-
dependent immune responses. Previous work on antigen uptake and presentation by …
dependent immune responses. Previous work on antigen uptake and presentation by …