Simulation of spatial learning in the Morris water maze by a neural network model of the hippocampal formation and nucleus accumbens

MA Brown, PE Sharp - Hippocampus, 1995 - Wiley Online Library
Cells in the hippocampal formation show spatial firing correlates thought to be critical to the
role played by this structure in spatial learning. Place cells in the hippocampus proper show …

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning

YY Huang, ER Kandel, L Varshavsky, EP Brandont… - Cell, 1995 - cell.com
Using a genetic approach, we assessed the effects of mutations in protein kinase A (PKA) on
long-term potentiation (LTP) in the mossy fiber pathway and its relationship to spatial and …

Hippocampal and nonhippocampal contributions to place learning in rats.

RJ McDonald, NM White - Behavioral neuroscience, 1995 - psycnet.apa.org
Brain structures thought to be critical for learning and memory were lesioned, and the effects
on rats' ability to locate food on a radial maze in situations that provided different types of …

Selective lesioning of the basal forebrain cholinergic system by intraventricular 192 IgG–saporin: Behavioural, biochemical and stereological studies in the rat

G Leanza, OG Nilsson, RG Wiley… - European Journal of …, 1995 - Wiley Online Library
The elucidation of the functional role of the basal forebrain cholinergic system will require
access to a highly specific and efficient cholinergic neurotoxin. Recently, selective depletion …

Posttraumatic brain hypothermia provides protection from sensorimotor and cognitive behavioral deficits

HM BRAMLETT, EJ GREEN, WD DIETRICH… - Journal of …, 1995 - liebertpub.com
The purpose of this study was to determine the degree of sensorimotor and cognitive
protection conferred by posttraumatic brain hypothermia. Baseline measurements were …

Entorhinal-perirhinal lesions impair performance of rats on two versions of place learning in the Morris water maze.

AH Nagahara, T Otto, M Gallagher - Behavioral neuroscience, 1995 - psycnet.apa.org
The effects of entorhinal–perirhinal lesions in rats were studied with 2 versions of a place
learning task in the Morris water maze. These lesions impaired performance on a multiple …

8-OH-DPAT impairs spatial but not visual learning in a water maze by stimulating 5-HT1A receptors in the hippocampus

M Carli, R Luschi, P Garofalo, R Samanin - Behavioural brain research, 1995 - Elsevier
The effect of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a 5-HT1A receptor
agonist, on spatial and non-spatial learning in a water maze was studied using two tasks of …

Prefrontal cortical mediation of rats' place learning in a modified water maze

J Mogensen, TK Pedersen, S Holm, LE Bang - Brain research bulletin, 1995 - Elsevier
The acquisition of a place learning task in a water maze modified from the “standard” set-up
by restriction of distal cues and addition of “proximal” cues (ping-pong balls in fixed positions …

Dentate gyrus destruction and spatial learning impairment after corticosteroid removal in young and middle‐aged rats

CD Conrad, EJ Roy - Hippocampus, 1995 - Wiley Online Library
We investigated the functional and behavioral implications of chronic corticosteroid removal
in young and middle‐aged rats. Prepubertal and 13‐month‐old rats were adrenalectomized …

Changes in the neonatal gonadal hormonal environment prevent behavioral sparing and alter cortical morphogenesis after early frontal cortex lesions in male and …

B Kolb, J Stewart - Behavioral Neuroscience, 1995 - psycnet.apa.org
The effects of perinatal exposure to testicular hormones were studied in male and female
rats given medial prefrontal cortical (PFC) lesions on Postnatal Day 7. Hormonally intact rats …