UV light as a footprinting agent: modulation of UV-induced DNA damage by transcription factors bound at the promoters of three human genes

S Tornaletti, GP Pfeifer - Journal of molecular biology, 1995 - Elsevier
Protein-DNA interactions in mammalian cells can be analyzed at the nucleotide level of
resolution by genomic sequencing techniques. The most sensitive genomic sequencing …

Mammalian nucleotide excision repair

L Ma, JHJ Hoeijmakers, AJ van der Eb - Biochimica et Biophysica Acta …, 1995 - Elsevier
The integrity of the genetic material is perpetually endangered by the chemical instability of
its primary structure and exposure to physical and chemical agents. Solar UV irradiation …

[HTML][HTML] Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain …

H Rodriguez, R Drouin, GP Holmquist… - Journal of Biological …, 1995 - ASBMB
The ligation-mediated polymerase chain reaction was used to map the frequency of reactive
oxygen species-induced DNA damage at nucleotide resolution in genomic DNA purified …

[HTML][HTML] Repair of UV-induced (6-4) photoproducts in nucleosome core DNA

C Suquet, DL Mitchell, MJ Smerdon - Journal of Biological Chemistry, 1995 - ASBMB
Using radioimmunoassays, we examined rates of removal of UV-induced pyrimidine-
pyrimidone) photoproducts ((6-4) PDs) and cyclobutane pyrimidine dimers (CPDs) from 146 …

UV-induced mutagenesis in the endogenous hprt gene and in hprt cDNA genes integrated at different positions of the human genome

EGR Lichtenauer-Kaligis, J Thijssen, H den Dulk… - Mutation Research …, 1995 - Elsevier
The influence of the genomic position of a gene on UV-induced mutations was studied in the
endogenous hprt gene in human lymphoblastoid TK6 cells and in cell lines derived from …

[HTML][HTML] Variations in transcription-repair coupling in mouse cells

AO Murad, J de Cock, D Brown, MJ Smerdon - Journal of Biological …, 1995 - Elsevier
Formation and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) was examined
in three different genes in mouse L cells: 1) a stably integrated insert (called LTL), consisting …

[图书][B] Risk factors in human and experimentally-induced large bowel cancer

PE Jackson - 1995 - search.proquest.com
The promutagenic lesion O6-methylguanine (O6-MeG) has been detected in human
colorectal tissue and the formation of such adducts in DNA following exposure to alkylating …

[图书][B] Cloning of methyltransferase cDNAs from Pisum sativum

M Cummings - 1995 - search.proquest.com
A number of approaches were adopted to clone pea MTase cDNAs. The only successful
approach, however, was PCR amplification of pea MTase-specific segments using …