Ito cells, perisinusoidal mesenchymal elements with possible pericytic functions within the
liver, recently have been shown to play multiple physiological and pathophysiological roles …

Irecent years we have witnessed a dramatic increase in our knowledge of the characteristics
and functions of liver nonparenchymal cells. In particular, much attention has been focussed …

Background & Aims: Hepatic lipocyte proliferation and activation are pivotal in liver fibrosis.
Disruption of normal lipocyte-matrix interactions may contribute to this process. The …

In 1987, a tremendous boost in our understanding of the action of dietary vitamin A occurred
with the discovery and characterization of nuclear receptors for retinoic acid, the active form …

Vitamin A is stored in the lipid droplets of liver stellate cells (LSCs), as retinyl esters whose
hydrolysis is necessary for the secretion of retinol into the blood. Here, we isolated these …

Although a low plasma high-density lipoprotein cholesterol (HDL-C) level is a well-accepted
risk factor for coronary artery disease (CAD), it is unclear whether pharmacologic agents can …

The action of the Na+/H+ antiport monensin on vitamin A uptake by rat liver has been
studied in vivo. The quickfading autofluorescence of vitamin A has been used for the …

Abstract The retinoid N-(4-Hydroxyphenyl) retinamide (HPR) effectively inhibits multiple
epithelial derived cancers. HPR rapidly depresses plasma retinol and retinol-binding protein …