Over the past years, evidence has been accumulating for a fundamental role of protein-
protein interactions between transcription factors in gene-specific transcription regulation …

The specificity of expression in the liver of the human apolipoprotein (apo) E/CI gene locus
is determined by a hepatic control region (HCR) that is located 15 kilobases downstream of …

The human coagulation protease factor VII plays a pivotal role in the initiation of the
coagulation cascade by both the extrinsic and the intrinsic pathway. Although the gene …

Liver-specific expression of the apolipoprotein AI (apoAI) gene is mediated by transcription
factors bound to three sites (A, B, and C) in the apoAI enhancer. Sites A and C bind various …

We have used apolipoprotein genes to investigate the signal transduction mechanisms
involved in the control of intestinal specific gene expression. The human apoAI, apoCIII, and …

Studies using transgenic mice indicate that expression of the human apolipoprotein (apo) AI
gene in the liver and small intestine is controlled by spatially distinct cis-acting DNA …

The induction of major histocompatibility complex class II gene expression is mediated by
three DNA elements in the promoters of these genes (W, X, and Y boxes). The Y box …

The PU. 1 protein is an ets-related transcription factor that is expressed in macrophages and
B lymphocytes. We present evidence that PU. 1 binds to the promoter of the I-Aβ gene, ie a …

Retinoids are reported to stimulate apolipoprotein (apo) AI gene promoter activity (Rottman
et al. 1991. Mol. Cell. Biol. 11: 3814-3820) and apoA-I protein secretion by monkey …

A fractionation of the membrane extract of rat testes revealed the existence of pp60c-src
kinase activity. The expression of pp60c-src was examined in the developing rat testes. The …