Apoptosis: molecular regulation of cell death

AJ Hale, CA Smith, LC Sutherland… - European Journal of …, 1996 - Wiley Online Library
The field of apoptosis is unusual in several respects. Firstly, its general importance has been
widely recognised only in the past few years and its surprising significance is still being …

Neutralizing antibodies to different proteins of African swine fever virus inhibit both virus attachment and internalization

P Gomez-Puertas, F Rodriguez, JM Oviedo… - Journal of …, 1996 - Am Soc Microbiol
African swine fever virus induces in convalescent pigs antibodies that neutralized the virus
before and after binding to susceptible cells, inhibiting both virus attachment and …

An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host …

PP Powell, LK Dixon, RM Parkhouse - Journal of virology, 1996 - Am Soc Microbiol
Cytokines stimulate inflammatory defenses against viral infections. In order to evade host
defenses, viruses have developed strategies to counteract antiviral cytokines. African swine …

An African swine fever virus virulence-associated gene NL-S with similarity to the herpes simplex virus ICP34. 5 gene

L Zsak, Z Lu, GF Kutish, JG Neilan, DL Rock - Journal of virology, 1996 - Am Soc Microbiol
We described previously an African swine fever virus (ASFV) open reading frame, 23-NL, in
the African isolate Malawi Lil 20/1 whose product shared significant similarity in a carboxyl …

An African swine fever virus Bc1-2 homolog, 5-HL, suppresses apoptotic cell death

CL Afonso, JG Neilan, GF Kutish, DL Rock - Journal of virology, 1996 - Am Soc Microbiol
Here, we show that the African swine fever virus 5-HL gene is a highly conserved viral gene
and contains all known protein domains associated with Bcl-2 activity, including those …

Evasion of apoptosis by DNA viruses

S Cuff, J Ruby - Immunology and cell biology, 1996 - Wiley Online Library
Apoptosis is a form of cell death distinct from necrosis which plays an important role in
processes such as homoeostasis and the elimination of damaged cells. It can be triggered …

Apoptosis: a mechanism of cell killing and lymphoid organ impairment during acute African swine fever virus infection

F Ramiro-Ibáñez, A Ortega… - Journal of General …, 1996 - microbiologyresearch.org
Induction of programmed cell death has been described during infection with many different
viruses. We have investigated the influence of African swine fever virus (ASFV) on apoptosis …

The Three-dimensional Structure of Mammalian Ribonucleotide Reductase Protein R2 Reveals a More-accessible Iron-radical Site thanEscherichia coliR2

B Kauppi, BB Nielsen, S Ramaswamy, IK Larsen… - Journal of molecular …, 1996 - Elsevier
The three-dimensional structure of mouse ribonucleotide reductase R2 has been
determined at 2.3 Å resolution using molecular replacement and refined to anR-value of …

Involvement of the endoplasmic reticulum in the assembly and envelopment of African swine fever virus

C Cobbold, JT Whittle, T Wileman - Journal of virology, 1996 - Am Soc Microbiol
African swine fever (ASF) virus is a large enveloped DNA virus assembled in the cytoplasm
of cells. In this study, the membrane compartments involved in the envelopment of ASF virus …

Strong sequence conservation of African swine fever virus p72 protein provides the molecular basis for its antigenic stability

M Yu, CJ Morrissy, HA Westbury - Archives of virology, 1996 - Springer
The major capsid protein p72 of African swine fever virus (ASFV) has long been considered
an important immunodominant antigen for serologic diagnosis. Here we describe the …