In the human species, three major histocompatibility complex (MHC) class I genes (HLA-A,-
B,-C), referred to as “classical” or “class Ia”, encode extremely polymorphic glycoproteins …

Fig. I. Proposed structures of putative HLA-G proteins (al dedrlrrcedjmn alternatively spkced
tran-scripts,(b) HLA-GZ protein errcoded by full-length MENA associates wikh &-m and has a …

PROBLEM: Human leukocyte antigen‐G (HLA‐G) is suggested to be at play in the materno‐
fetal immune relationship during pregnancy. In the light of current concept that disruption of …

Background: The physiological functions of the classical HLA (human leukocyte antigen)
molecules, HLA-A, HLA-B and HLA-C, are to present peptides to T cells and to inhibit the …

Mutating the HLA-A* 0201 heavy chain from threonine to lysine at position 134 (T134K)
results in a molecule that presents exogenous peptide, but cannot present endogenously …

Background: Glycoproteins encoded by the major histocompatibility complex class I region
(MHC class I) present peptide antigens to cytotoxic T cells (CTLs). Peptides are delivered to …

HLA-G is a class I gene that is expressed in the extravillous cytotrophoblast. Although the
function of this gene is still unknown, its expression at the maternal-fetal interface suggests …

Three known lineages of antigen-presenting molecules restrict T-cell responses to microbial
antigens: MHC class I and MHC encoded class I like molecules present peptides derived …

One of the hallmarks of the vertebrate major histocompatibility complex (MHC) class I gene
families is their remarkable plasticity. The number of class I genes, their organization …

Immunology: Keeping mother at bay: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …