Publisher Summary Human repeats have been largely identified and cataloged, accounting
for a substantial fraction of the genome. Repetitive sequences are ubiquitously interspersed …

Precise mapping of DNA methylation patterns in CpG islands has become essential for
understanding diverse biological processes such as the regulation of imprinted genes, X …

It has been a controversial issue as to how many DNA cytosine methyltransferase
mammalian cells have and whether de novo methylation and maintenance methylation …

A number of aberrant morphological phenotypes were noted during propagation of the
Arabidopsis thaliana DNA hypomethylation mutant, ddm1, by repeated self-pollination …

Parental (genomic) imprinting is the process by which the differential expression of maternal
and paternal alleles at certain genetic loci in mammalian embryos occurs. Such loci are …

Embryonic stem (ES) cells homozygous for a disruption of the DNA (cytosine-5)-
methyltransferase gene (Dnmt) proliferate normally with their DNA highly demethylated but …

The human SNRPN (small nuclear ribonucleoprotein polypeptide N) gene is one of a gene
family that encode proteins involved in pre-mRNA splicing and maps to the smallest deletion …

In mammals, the maternal and paternal genomes are required for embryonic development1–
5. This is due to genomic imprinting which leads to the expression or repression of genes …

Normal mammalian development requires a diploid combination of both haploid parental
genomes1. Uniparental disomy for certain segments of specific chromosomes results in …

Methylation of cytosine residues in mammalian DNA is established during gametogenesis
and embryogenesis; it plays an important role in gene regulation and normal embryonic …