We have recently reported that a 16-amino acid long polypeptide corresponding to the third
helix of the DNA binding domain (homeodomain) of Antennapedia, a Drosophila …

We have developed a lipidic gene transfer vector, LPDII, where DNA was first complexed to
polylysine at a ratio of 1: 0.75 (w/w) and then entrapped into folate-targeted pH-sensitive …

The vitamin folic acid was covalently linked to the chelating agent deferoxamine (DF) via an
amide bond using a simple carbodiimide coupling reaction. A mixture of two isomers, DF …

Free folic acid is believed to enter some cells by folate receptor-mediated endocytosis at
membrane invaginations termed caveolae. Folate conjugated macromolecules also enter …

The receptor-mediated endocytosis uptake pathway for the vitamin folate was investigated
as a target for tumor-selective radiopharmaceutical delivery. The molecular target for this …

I. INTRODUCTION The mamm~ dian lymph nodes are aggregates of finely structured
lympho-reticular tissues. These structures are placed at intervals along the lymphatic …

1. Field of the Invention This invention relates to agents and therapy to lessen morbidity and
mortality by protecting against septic shock, Adult Respiratory Distress Syndrome (ARDS) …

Receptor-mediated endocytosis (RME) which plays an important role in the elimination of
biologically active polypeptide can be utilized as a target of the drug delivery system (DDS) …

Purpose. Conjugation of bovine serum albumin (BSA) with riboflavin (BSA-riboflavin)
increases its uptake into cultured epithelial cells. Our purpose was to determine whether …

The syntheses of biodegradable 2′‐and 5′‐ester and 2′‐and 5′‐carbonate conjugates
of the antivirally active 3′‐deoxyadenylyl‐(2′–5′)‐3′‐deoxyadenylyl‐(2′–5′)‐3 …