Agarose gel electrophoresis for DNA damage analysis

R Drouin, S Gao, GP Holmquist - … for detection of DNA damage and …, 1996 - Springer
Physical and chemical mutagens induce frank breaks in DNA which reduce its single-strand
molecular weight. Other nonbreak lesions in the DNA can often be converted into strand …

Ligation-mediated PCR for analysis of oxidative DNA damage

R Drouin, H Rodriguez, GP Holmquist… - Technologies for detection …, 1996 - Springer
Reactive oxygen species (ROS), including Superoxide anion, hydrogen peroxide (H 2 O 2),
hydroxyl radical, and singlet oxygen, may play an important role in promoting aging and …