Interleukin 8, the first chemokine to be characterized, was discovered nearly ten years ago.
Today, more than 30 human chemokines are known. They are often upregulated in …

Glucocorticoids are powerful regulators of immune function. Their role in reducing
inflammation and autoimmune responses is well known, as is their ability to induce …

Chemokines have been convincingly implicated in actuating inflammatory leukocyte
emigration. To affect the circulating leukocytes, tissue-derived chemokines have to traverse …

Protein and lipid glycosylation is no longer considered as a topic whose appeal is restricted
to a limited number of analytical experts perseveringly pursuing the comprehensive …

The scope of cytokine biology is fascinating with widespread applications anticipated in
many areas of medical science. We have emphasized the fundamental roles that cytokines …

Background Inflammatory and coagulation processes are both affected in
meningococcaemia. Severe acquired protein-C deficiency in meningococcaemia is usually …

Midkine (MK) is a retinoic acid-inducible heparin-binding cytokine. In the inflammatory
synovitis of rheumatoid arthritis and osteoarthritis, MK was detected in synovial fluid …

Yeast protein, Bee1, exhibits sequence homology to Wiskott-Aldrich syndrome protein
(WASP), a human protein that may link signaling pathways to the actin cytoskeleton …

Escherichia coli stimulates neutrophil migration across human uroepithelial cell layers. This
study investigated the role of the neutrophil chemokine interleukin-8 (IL-8) in this process. E …

This study examines the role of L-selectin in monocyte adhesion to arterial endothelium, a
key pathogenic event of atherosclerosis. Using a nonstatic (rotation) adhesion assay, we …