Interleukin-6 (IL-6), a member of the neuropoietic cytokine family, initially was described in
terms of its activities in the immune system and during inflammation. Accumulating evidence …

Abstract The cytokine interleukin-6 (IL-6) is an important mediator of inflammatory and
immune responses in the periphery. IL-6 is produced in the periphery and acts systemically …

Background and Purpose Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine that
rapidly upregulates in the brain after injury. The present study was designed to explore the …

Recent studies have demonstrated the essential role of tumor necrosis factor a (TNF-α) in
rheumatoid arthritis and Crolin's disease. This article discusses agents known to suppress …

✓ Subarachnoid hemorrhage (SAH) causes an inflammatory reaction and may lead to
ischemic brain damage. Experimental ischemia has been shown to be connected with the …

It has been reported that middle cerebral artery occlusion in rats causes overexpression of
interleukin-1, and that administration of the interleukin-1 receptor antagonist protein (IL-1ra) …

The levels of tumor necrosis factor (TNF)-α, soluble TNF receptors p75 (sTNFR-75) and
sTNFR-55, interferon (IFN)-γ, and interleukin (IL)-10 and IL-12 were measured in 59 …

In humans, bacterial toxins induce the systemic inflanmatory response syndrome (SIRS),
which often results in fatal shock. the pathophysiology of this complex process involves …

Using in situ hybridization with radiolabelled oligonucleotide probes, we studied the mRNA
expression of IL-1β, IL-4, IL-6, IL-10, IL-12, tumour necrosis factor-alpha (TNF-α), TNF-β …

Inflammation in the subarachnoid space represents the pathological hallmark of bacterial
meningitis. The intrathecal accumulation of leukocytes, in response to bacterial pathogens …