抄録 The biological activities of 7 microbial extracellular glycolipids including
mannosylerythritol lipid (MEL)-A, MEL-B, polyol lipid (PL), rhamnolipid (RL), sophorose lipid …

Microbial extracellular glycolipids, succinoyl trehalose lipid (STL), and mannosylerythritol
lipid (MEL) inhibited the growth of a human promyelocytic leukemia cell line, HL60, and …

Gangliosides are believed to play a critical role in cellular differentiation. To test this concept,
we determined the effect of inhibition of endogenous ganglioside synthesis upon neurite …

Gangliosides are known to be differentiation-inducing molecules in mammalian stem cells.
We studied the interaction between the molecular structure of glycosphingolipids (GSLs) …

Incorporation and metabolism of exogenous GM3 in human myelogenous leukemia HL‐60
cells were analyzed using 3H‐labeled GM3 ([3H] GM3).[3H] GM3 was rapidly internalized …

Exogenous neutral glycosphingolipids induced homotypic cell‐cell aggregation of a variety
of hematopoietic cell lines. A mouse cytotoxic T cell line, CTLL‐2, was chosen to study the …

The functional studies of glycosphingolipids in hematology and immunology fields have
been discussed in this review. First,(1) Glycolipid antigens known as cell surface …

Gangliosides, added exogenously at concentrations of 10–100 μM, inhibit intrinsic protein
kinase activities in purified rat brain myelin. Multivalent neoganglioproteins–gangliosides …

Incorporation and metabolism of exogenous GM3 in human myelogenous leukemia HL-60
cells were analyzed using 3H-labeled GM3 ([3H) GM3).[3H) GM3 was rapidly internalized …

本稿では, 血液学・免疫学両分野での糖脂質の機能研究につき, 我々の研究成果に触れながら解説
を試みたい. まず, ヒト白血球分化抗原としての糖脂質糖鎖についてまとめたあと …