Objectives: To evaluate possible inconsistencies between recommended, actual and
desired folate intake in European adult populations. Design: Review of dietary …

Infant mortality has long been viewed as a synoptic indicator of the health and social
condition of a population. In this article we examine critically the structure of this reflective …

Folate deficiency causes massive incorporation of uracil into human DNA (4 million per cell)
and chromosome breaks. The likely mechanism is the deficient methylation of dUMP to …

Background Although a daily supplement of 400 μg folic acid has been shown to prevent
neural-tube defects (NTD), most women do not take the recommended supplement. Thus …

Many rheumatic maternal diseases occur in women during their childbearing years.
Treatment is frequently necessary before, during, and after pregnancy to maximize the …

There is accumulating evidence that periconceptional multivitamin use may prevent the
occurrence of some birth defects other than neural tube defects. Using data from the …

Objective.—To identify predictors of red cell folate level in women attempting to become
pregnant. Design.—Cohort study. Setting.—A health maintenance organization serving the …

Pregnancy and lactation are periods when maternal reserves of choline are depleted. At the
same time, the availability of choline for normal development of brain is critical. Variations in …

Vitamins play an important role in intermediary metabolism as co-factors in numerous
enzymatic reactions or in non-enzymatic physiological functions such as the visual process …

The potential role for folic acid in preventative medicine is reviewed under the following
headings: biochemistry and nomenclature; homocysteine-a new independent risk factor for …