Molecules involved in mammalian sperm-egg interaction

SB McLeskey, C Dowds, R Carballada… - International Review of …, 1997 - Elsevier
To achieve fertilization, sperm and egg are equipped with specific molecules which mediate
the steps of gamete interaction. In mammals, the first interaction between sperm and egg …

Characterization of the binding of recombinant mouse sperm fertilin β subunit to mouse eggs: Evidence for adhesive activity via an egg β1integrin-mediated interaction

JP Evans, GS Kopf, RM Schultz - Developmental biology, 1997 - Elsevier
The sperm protein fertilin (also known as PH-30) is a candidate for mediating the
interactions between sperm and egg plasma membranes. Fertilin is a heterodimer. The β …

Acrosome-intact boar spermatozoa initiate binding to the homologous zona pellucida in vitro

A Fazeli, WJ Hage, FP Cheng… - Biology of …, 1997 - academic.oup.com
The acrosome reaction is a prerequisite for zona pellucida penetration by mammalian
spermatozoa. In some species, the sperm undergo the acrosome reaction before binding to …

Mutant female mice carrying a single mZP3 allele produce eggs with a thin zona pellucida, but reproduce normally

PM Wassarman, H Qi… - Proceedings of the …, 1997 - royalsocietypublishing.org
The mouse egg zona pellucida (ZP) is composed of three glycoproteins, called mZP1− 3.
Disruption of the mZP3 gene by targeted mutagenesis yields mice that are homozygous …

A major glycoprotein of Xenopus egg vitelline envelope, gp41, is a frog homolog of mammalian ZP3

H Kubo, T Kawano, S Tsubuki… - Development …, 1997 - Wiley Online Library
A predominant glycoprotein in the vitelline envelope (VE) of the anuran Xenopus laevis is
gp41, known to be proteolytically converted from gp43 of the coelomic egg envelope …

Identification of bovine zona pellucida glycoproteins

EK Topper, L Kruijt, J Calvete, K Mann… - Molecular …, 1997 - Wiley Online Library
Despite the economical importance of in vitro gamete technologies in cattle, only little is
known about the molecular mechanisms of binding of spermatozoa to the zona pellucida …

Protein kinase C plays an important role in the human zona pellucida-induced acrosome reaction.

DY Liu, HW Baker - Molecular human reproduction, 1997 - academic.oup.com
To investigate the involvement of protein kinases in signal transduction in the human zona
pellucida (ZP)-induced acrosome reaction (AR), the effects of protein kinase (PK) activators …

Modifications of carbohydrate residues and ZP2 and ZP3 glycoproteins in the mouse zona pellucida after fertilization

M Avilés, L Jaber, M Teresa Castells… - Biology of …, 1997 - academic.oup.com
Oligosaccharide side chains of zona pellucida (ZP) glycoproteins play a key role in the
sperm-egg interaction phenomena during fertilization. In the present study, modifications of …

Heterogeneity of the zona pellucida carbohydrate distribution in human oocytes failing to fertilize in vitro.

R Talevi, R Gualtieri, G Tartaglione… - Human reproduction …, 1997 - academic.oup.com
The mammalian zona pellucida contains several glycoproteins whose oligosaccharide
moieties are known to play a key role in the interaction with spermatozoa. Since zona …

Interaction of acrosome-reacted macaque sperm with the macaque zona pellucida

CA VandeVoort, AI Yudin… - Biology of …, 1997 - academic.oup.com
In this study we investigated the ultrastructure of macaque sperm induced to acrosome-react
with calcium ionophore A23187, and the interaction between these acrosome-reacted …