Dosage compensation for X-linked genes in mammals is accomplished by inactivating one
of the two X chromosomes in females. X-chromosome inactivation (XCI) occurs during …

The gamma-glutamyl transpeptidases are key enzymes in the so-called gamma-glutamyl
cycle involving glutathione synthesis, the recovery of its constituents, and in the transport of …

Fig. 1 Sequence alignments, structures and expression patterns of mouse Dnmt3a and
Dnmt3b. a, Sequences of Dnmt3α and Dnmt3β. Identical amino-acid residues are shaded …

Les auteurs ont récemment rapporté que la formation d'allopolyploïdes chez le blé s'
accompagnait de l'élimination rapide et non-aléatoire de séquences non-codantes …

DNA methylation is essential for normal embryonic development. Distinctive genomic
methylation patterns must be formed and maintained with high fidelity to ensure the …

Observations made with Escherichia coli have suggested that a lag between replication and
methylation regulates initiation of replication. To address the question of whether a similar …

Nonmethylated CpG islands are generally located at the 5′ ends of genes, but a CpG
island in the mouse major histocompatibility complex class II I-Aβ gene is remote from the …

Gene expression is under the influence of DNA methylation and assembly of chromatin
structure. This paper reports the modulation of transgene expression in zebrafish embryos …

This study describes the clinical spectrum of patients with Klinefelter's syndrome and
seizures. Klinefelter's syndrome is a sex chromosomal abnormality and the most common …

DNA (cytosine-5-)-methyltransferase is essential for viable mammalian development and
has a central function in the determination and maintenance of epigenetic methylation …