APPROXIMATELY 10,000 autologous hematopoietic stem cell (HSC) transplants are
performed worldwide each year for malignant diseases. 1 Results of randomized trials in …

Dendritic cells (DCs) are professional antigen presenting cells with the unique capacity to
induce primary and secondary immune responses in vivo. Here, we show that DCs secrete …

DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood
to the tissues where, while immature, they capture antigens. They then leave the tissues and …

Dendritic cells (DC) are thought to initiate Ab synthesis by activation of T cells, which then
provide cytokine and cell-bound “help” to B cells. Here, we provide evidence that DC can …

Naive T cells can become either tolerant or immune as a result of their first encounter with
antigen. It has been suggested that lymphoid and myeloid dendritic cells, respectively …

Asthma is characterized by chronic eosinophilic inflammation of the airways, and allergen-
specific Th2 lymphocytes are thought to play a major role in the development and …

Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid
organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity. However, the …

Dendritic cells (DC) are potent APCs initiating immune responses. In a previous report, we
demonstrated that DC directly enhance both proliferation and differentiation of CD40 …

The generation of Abs recognizing the native structure of the human thyrotropin receptor
(hTSHR) has been difficult because there is currently no method allowing the purification of …

Hepatitis B virus (HBV) transgenic mice that are immunologically tolerant to HBV-encoded
Ags represent a model of chronic HBV infection suitable for the development of therapeutic …