A number of recent studies have provided new insights into mechanisms that regulate
genomic imprinting in the mammalian genome. Regions of allele-specific differential …

DNA methylation patterns were evaluated during preimplantation mouse development by
analyzing the binding of monoclonal antibody to 5-methylcytosine (5-MeC) on metaphase …

CpG islands are G+ C‐rich regions∼ 1 kb long that are free of methylation and contain the
promoters of many mammalian genes. Analysis of in vivo replication intermediates at three …

Androgen-independent metastatic prostate cancer is characterized by a heterogeneous loss
of androgen receptor (AR) expression among tumor cells. In this study, we evaluate DNA …

Both DNA methylation and hypoacetylation of core histones are frequently associated with
repression of gene expression. Possible connections between these processes were …

Three different kinds of alterations in DNA methylation have been observed in urological
malignancies. DNA hypermethylation of CpG-rich promoter regions is an important …

The cell cycle regulatory gene cyclin D1 is a candidate oncogene in breast cancer. It is
overexpressed in 30-50% of invasive primary breast cancers and plays a key role in …

Human leukosialin (CD43) is expressed in a cell lineage-specific as well as a differentiation
stage-specific fashion. The leukosialin promoter, made up of an Sp1 binding site and a …

Using methylation-sensitive restriction enzymes, we characterized the methylation pattern
on the 5′ side of the CTG repeat in the DMPK gene of normal individuals and of patients …

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is indispensable for viral DNA
replication and episome maintenance in latency. Four promoters, Cp, Wp, Qp, and Fp, are …