Signaling by the secreted hedgehog, decapentaplegic and wingless proteins organizes the
pattern of photoreceptor differentiation within the Drosophila eye imaginal disc; hedgehog …

This study describes the isolation and characterization of zebrafish homologues of the
mammalian Pax3 and Pax7 genes. The proteins encoded by both zebrafish genes are …

It has been demonstrated previously that Pax-6, a paired domain (PD)/homeodomain (HD)
transcription factor critical for eye development, contributes to the activation of the αB-, αA …

Redox potential controls the DNA-binding activity of several transcription factors. In some
cases, the regulation of DNA-binding activity by the redox state is mediated by the Ref-1 …

Pax proteins are transcriptional regulators controlling a variety of cell fates during animal
development. This role depends on the intact function of the paired (Prd) domain that is able …

Pax proteins, characterized by the presence of a paired domain, play key regulatory roles
during development. The paired domain is a bipartite DNA-binding domain that contains two …

What are the developmental mechanisms required for conversion of an undifferentiated, two-
dimensional field of cells into a patterned, tubular organ? In this report, we describe the …

Abstract vsx1 is a homeobox gene encoding a paired‐type homeodomain and a CVC
domain that was originally cloned from an adult goldfish retinal library. We previously …

Pax-3, a transcription factor that is required for development of the embryonic neural tube,
neural crest, and somitic derivatives, contains two DNA-binding domains, a paired domain …

ABSTRACT ζ-Crystallin is a taxon-specific crystallin, an enzyme which has undergone direct
gene recruitment as a structural component of the guinea pig lens through a Pax6 …