Publisher Summary This chapter focuses on the chemical mutagenesis procedure and
screening strategies for efficient induction and recovery of developmental mutations in the …

A bone morphogenetic protein (BMP) signaling pathway is implicated in dorsoventral
patterning inXenopus. Here we show that three genes in the zebrafish, swirl, snailhouse …

The zebrafish one-eyed pinhead (oep) mutation disrupts embryonic development, resulting
in cyclopia and defects in endoderm, prechordal plate, and ventral neuroectoderm …

Inhibition of fibroblast growth factor (FGF) signaling prevents trunk and tail formation in
Xenopus and zebrafish embryos. While the T-box transcription factor Brachyury (called No …

Zebrafish paraxial protocadherin (papc) encodes a transmembrane cell adhesion molecule
(PAPC) expressed in trunk mesoderm undergoing morphogenesis. Microinjection studies …

Signals from the organizer play a crucial role in patterning the vertebrate embryo. Recent
molecular analysis of zebrafish mutations has established an essential role for BMP2 and …

Vertebrate eye development in the anterior region of the neural plate involves a series of
inductive interactions dependent on the underlying prechordal plate and signals from the …

In vertebrates, the segmented somites, which are the medial-most component in the paraxial
mesoderm, are the entity giving rise to the axial bones and skeletal muscles. We previously …

The patterning activity of the Spemann organizer in early amphibian embryos has been
characterized by a number of organizer-specific secreted proteins including Chordin …

Publisher Summary Cellular and molecular mechanisms involved in the establishment of the
zebrafish embryonic body plan appear strikingly similar to those operating in amphibians or …